hired is a large gold prospecting area which is located in south khorasan province, in the east of iran. gold mineralization is found in 4 target areas covering about 24 km2. the host rocks are mainly tertiary volcanics, some jurassic and cretaceous sediments. sub-volcanic rocks are of magnetite series (gabbros to diorite) and ilmenite series (granite-granodiorite-monzonite) which have intruded...

Recent technologies like AGO CLIP sequencing and CLASH enable direct transcriptome-wide identification of AGO binding and miRNA target sites, but the most widely used miRNA target prediction algorithms do not exploit these data. Here we use discriminative learning on AGO CLIP and CLASH interactions to train a novel miRNA target prediction model. Our method combines two SVM classifiers, one to p...

MOTIVATION During the last few years, several new small regulatory RNAs (sRNAs) have been discovered in bacteria. Most of them act as post-transcriptional regulators by base pairing to a target mRNA, causing translational repression or activation, or mRNA degradation. Numerous sRNAs have already been identified, but the number of experimentally verified targets is considerably lower. Consequent...

MicroRNAs (miRNAs) are an important class of small noncoding RNAs capable of regulating other genes' expression. Much progress has been made in computational target prediction of miRNAs in recent years. More than 10 miRNA target prediction programs have been established, yet, the prediction of animal miRNA targets remains a challenging task. We have developed miRecords, an integrated resource f...

Sensory feedback is very important for movement control. However, feedback information has not been directly used to update movement prediction model in the previous BMI studies, although the closed-loop BMI system provides the visual feedback to users. Here, we propose a BMI framework combining image processing as the feedback information with a novel prediction method. The feedback-prediction...

Two-level predictors deliver highly accurate conditional branch prediction, indirect branch target prediction and value prediction. Accurate prediction enables speculative execution of instructions, a technique that increases instruction level parallelism. Unfortunately, the accuracy of a two-level predictor is limited by the cost of the predictor table that stores associations between history ...

miRNAs are small non-coding RNAs that regulate gene expression by binding to the 3'-UTR of genes. Many recent studies have reported that miRNAs play important biological roles by regulating specific mRNAs or genes. Many sequence-based target prediction algorithms have been developed to predict miRNA targets. However, these methods are not designed for condition-specific target predictions and p...

To evaluate and predict component-based software security, a two-dimensional model of software security is proposed by Stochastic Petri Net in this paper. In this approach, the software security is modeled by graphical presentation ability of Petri nets, and the quantitative prediction is provided by the evaluation capability of Stochastic Petri Net and the computing power of Markov chain. Each...