نتایج جستجو برای: tarantula

تعداد نتایج: 381  

2014
Kristian W. Sanggaard Jesper S. Bechsgaard Xiaodong Fang Jinjie Duan Thomas F. Dyrlund Vikas Gupta Xuanting Jiang Ling Cheng Dingding Fan Yue Feng Lijuan Han Zhiyong Huang Zongze Wu Li Liao Virginia Settepani Ida B. Thøgersen Bram Vanthournout Tobias Wang Yabing Zhu Peter Funch Jan J. Enghild Leif Schauser Stig U. Andersen Palle Villesen Mikkel H. Schierup Trine Bilde Jun Wang

Spiders are ecologically important predators with complex venom and extraordinarily tough silk that enables capture of large prey. Here we present the assembled genome of the social velvet spider and a draft assembly of the tarantula genome that represent two major taxonomic groups of spiders. The spider genomes are large with short exons and long introns, reminiscent of mammalian genomes. Phyl...

2018
Feng Zhang Andres Jara-Oseguera Tsg-Hui Chang Chanhyung Bae Sonya M. Hanson Kenton J. Swartz

The TRPV1 channel is a sensitive detector of pain-producing stimuli, including noxious heat, acid, inflammatory mediators, and vanilloid compounds. Although binding sites for some activators have been identified, the location of the temperature sensor remains elusive. Using available structures of TRPV1 and voltage-activated potassium channels, we engineered chimeras wherein transmembrane regio...

2012
Shin Yoo

Spectra-Based Fault Localisation (SBFL) aims to assist debugging by applying risk evaluation formulæ (sometimes called suspiciousness metrics) to program spectra and ranking statements according to the predicted risk. Designing a risk evaluation formula is often an intuitive process done by human software engineer. This paper presents a Genetic Programming approach for evolving risk assessment ...

2017
David Wilson Glen M Boyle Lachlan McIntyre Matthew J Nolan Peter G Parsons Jennifer J Smith Leon Tribolet Alex Loukas Michael J Liddell Lachlan D Rash Norelle L Daly

Spider venoms constitute incredibly diverse libraries of compounds, many of which are involved in prey capture and defence. Polyamines are often prevalent in the venom and target ionotropic glutamate receptors. Here we show that a novel spider polyamine, PA366, containing a hydroxyphenyl-based structure is present in the venom of several species of tarantula, and has selective toxicity against ...

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