We congratulate Drs. Laber, Lizotte, Qian, Pelham and Murphy on an outstanding review of dynamic treatment regimes (DTRs). This group has done pioneering work in advancing the theory and applications of DTRs. In a DTR, the treatment type and level are repeatedly adjusted according to an individual’s need. An important part of designing DTRs is to choose tailoring variables. A tailoring variable...

To change applications to fit the needs for users, for different places and for development over time has long been a challenge called software maintenance. In this chapter we take up tailoring as a means to make software flexible. Starting with two case studies one taking up tailoring for different users and one addressing changes over time the article discusses the problems with both use and ...

aytheon Systems Company, a defense electronics firm, typifies many US Defense Department environments in its strong, process-oriented development strategy. The company has been actively engaged in software process improvement at the organizational and project levels for over a decade. Raytheon bases its efforts on the Software Engineering Institute's Capability Maturity Model, and our segment o...

Defining organizational software processes is essential for enhancing maturity because they cannot be improved if they are not specified. However, software process definition is hard and still not good for assuring productivity because the best process depends on the project’s particularities. The process engineer can define a specific process for each kind of project, but this is expensive, un...

An automatic test pattern generation (ATPG) method is presented for a scan-based test architecture which minimizes ATE storage requirements and reduces the bandwidth between the automatic test equipment (ATE) and the chip under test. To generate tailored deterministic test patterns, a standard ATPG tool performing dynamic compaction and allowing constraints on circuit inputs is used. The combin...

Chaos is a class of ubiquitous phenomena and controlling chaos is of great interest and importance. In this Letter, we introduce wavelet controlled dynamics as a new paradigm of dynamical control. We find that by modifying a tiny fraction of the wavelet subspaces of a coupling matrix, we could dramatically enhance the transverse stability of the synchronous manifold of a chaotic system. Wavelet...

Molecular biology is a rapidly evolving field that has led to the development of increasingly sophisticated technologies to improve our capacity to study cellular processes in much finer detail. Transcription is the first step in protein expression and the major point of regulation of the components that determine the characteristics, fate and functions of cells. The study of transcriptional re...

BACKGROUND Smoking, high alcohol consumption, unhealthy eating habits and physical inactivity often lead to (chronic) diseases, such as cardiovascular diseases and cancer. Tailored online interventions have been proven to be effective in changing health behaviours. The aim of this study is to test and compare the effectiveness of two different tailoring strategies for changing lifestyle compare...

Healthcare providers are moving towards tailoring self-management interventions to include the communication nology and involvement in managing chronic conditions will be critical for informing effective self-management strategies. The race, and education level that have been shown to negatively affect care. To inform the design and tailoring of selfmanagement interventions, we elicited attitud...

24 Aluminum coagulants are widely used in water treatment plants to remove turbidity and 25 dissolved substances. However, because high aluminum concentrations in treated water are 26 associated with increased turbidity and because aluminum exerts undeniable human health 27 effects, its concentration should be controlled in water treatment plants, especially in plants 28 that use aluminum coagu...