نتایج جستجو برای: tail flick test

تعداد نتایج: 858539  

Journal: :Brain research 1986
R M Levy H L Fields M P Stryker M M Heinricher

The effect of morphine on regional cerebral glucose metabolism was measured in rats using high resolution [14C]2-deoxyglucose autoradiography with concurrent confirmation of morphine-induced analgesia measured by tail-flick latency to noxious heat. Within the limits of resolution of this technique, doses of morphine sufficient to inhibit the tail-flick reflex had no significant effect on glucos...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه پیام نور - دانشگاه پیام نور استان تهران - دانشکده علوم پایه 1388

در مطالعه حاضر، اثر عصاره آبی- الکلی برگ و ساقه گیاه کاهوی ایرانی بر درد و التهاب در مدل tail-flick ، فرمالین تست و مدل گزیلن تست مورد بررسی قرار گرفته است. روش بررسی: در این مطالعه اثر ضد دردی عصاره آبی- الکلی برگ و ساقه کاهو با آزمون tail-flick و فرمالین تست در موش سوری نر مورد بررسی قرار گرفت. اثر ضد التهابی از طریق ایجاد التهاب در گوش توسط گزیلن مورد آزمایش قرار گرفت. به این منظور عصاره ک...

ژورنال: :یافته 0
مجتبی خاکساریان mojtaba khaksarian دانشگاه علوم پزشکی لرستان محمد هادی مشکوه السادات mohammad hadi meshkatosadat دانشگاه لرستانسازمان اصلی تایید شده: دانشگاه علوم پزشکی لرستان (lorestan university of medical sciences) رسول فرازی فرد rasoul farzi دانشگاه علوم پزشکی لرستانسازمان اصلی تایید شده: دانشگاه لرستان (lorestan university) فرزانه صفرپور farzaneh safarpour دانشگاه علوم پزشکی لرستانسازمان اصلی تایید شده: دانشگاه علوم پزشکی لرستان (lorestan university of medical sciences)

مقدمه : درگزارش های اخیر خواص ضددردی گیاه دارویی بن سرخ با استفاده از آزمونهای فرمالین و tail flick نشان داده شده است. بر همین اساس هدف این تحقیق بررسی و آنالیز مواد موجود در عصاره گیاه، آزمون حسی حرکتی و اثرات اوپیوئیدی قرار گرفت. مواد و روش ها: گیاه دارویی بن سرخ در ارتفاع 2200 متری منطقه سفید کوه لرستان در اردیبهشت ماه جمع آوری گردید و در دانشکده کشاورزی لرستان کد گزاری گردید. عصاره گیری با ...

Journal: :iranian journal of pharmaceutical sciences 0
naser mirazi department of biology, faculty of basic science, bu-ali sina university, hamedan, iran abdolkarim hosseini department of biology, faculty of basic science, bu-ali sina university, hamedan, iran

herbal medicine has an old history with a broad application all over the world. many researches have focused on the curative as well as antinociceptive effects of herbal extract. the aim of this study was to investigate the analgesic effects of berberis vulgaris hydroethanolic extract (bve) in male mice. 30 male mice were divided into 5 groups: control, treated by morphine, treated by bve (150 ...

Journal: :British journal of anaesthesia 1996
T Goto J J Marota G Crosby

We reported previously that nitrous oxide induces pre-emptive analgesia that is partially antagonized by naloxone and totally antagonized by halothane. The aims of this study were to determine if halothane and isoflurane are similar in this respect and to examine if volatile anaesthetics antagonize the analgesic effect of exogenous opioids. We found that 75% nitrous oxide prolonged tail-flick l...

Journal: :iranian journal of pharmaceutical research 0
v hajhashemi a ghannadi m hajiloo

extracts obtained from the petals of rosa damascena (rosaceae) are used in iranian folk medicine as remedies for the treatment of some inflammatory diseases. in this study the hydroalcoholic extract and essential oil of the plant were investigated for its possible anti-inflammatory and analgesic activities. the extract was administered at the doses (p.o.) of 250, 500 and 1000?mg/kg and the dose...

Journal: :basic and clinical neuroscience 0
meisam fadaei-kenarsary tea organization rest house, kelarabad, mazandaran, i.r.iran, postal code: 4673119573 yaghoob farbood ahvaz jundishapur university of medical sciences (ajums), school of medicine, department of pharmacology, physiology research center, ahvaz, i.r. iran. postal code: 61357-33118 seyed mohammad taghi mansouri ahvaz jundishapur university of medical sciences (ajums), school of medicine, department of pharmacology, physiology research center, ahvaz, i.r. iran. postal code: 61357-33118 hadi fathi moghaddam 84 mehran street, melirah ave, ahvaz, iran. po box: 61357-33118

introduction: methadone has been used as a drug to detoxify opioid tolerance. naloxane precipitated morphine withdrawal behaviours were attenuated by venlafaxine as an antidepressant. on the contrary, after detoxifying the opioids, spontaneous withdrawal syndrome may occur with pain sensitivity. therefore the present study aimed to examine the effects of chronic methadone (70 mg/kg, in drinking...

A Rashidy-Pour AA Taherian AA Vafaei H Sadeghi

Since use of antinoceceptive chemical drugs for relief of pain has many side effects, medical plants seem very noticeable today. Previous findings indicate that Carum Carvi (CC) modulates pain in both animal and human. The present work investigated the effects of hydoalcoholic extract of CC on acute pain in Hot plate and Tail flick models. Albino mice (20-30 g) were used for this study. Hydroal...

Journal: :The Journal of pharmacology and experimental therapeutics 1999
C J Bol J P Vogelaar J W Mandema

This study characterizes the anesthetic profile of dexmedetomidine on the basis of steady-state plasma concentrations using defined stimulus-response, ventilatory, and continuous electroencephalographic (EEG) and cardiovascular effect measures in rats. At constant plasma concentrations of dexmedetomidine (range, 0.5-19 ng/ml), targeted and maintained by target-controlled infusion, the whisker r...

A Sarihi B Heshmatian

Recent neuroanatomical and behavioral evidence has indicated that vasopressin (VA) increases pain threshold. The dorsal raphe nucleus (DRN) is an important nucleus in pain modulation. Anatomical studies have shown that DRN receives vasopressinergic fibers originating in the hypothalamic paraventricular nucleus. The aim of the present study was to examine the effects of intra-DRN injection of de...

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