Flow cytometry (FCM) was adapted to measure ploidy values in megakaryocytes isolated from normal guinea pigs and African green monkeys. The FCM approach was validated by microscopic identification of electronically sorted SN and higher ploidy cells and by comparisons with Feulgen microdensitometry on the same samples. Sorted 8N populations contained only megakaryocytes and were completely free ...

BACKGROUND Parkinson's disease is a degenerative disorder of the central nervous system resulting from neuronal loss in the substantia nigra (a region of the mid brain) and BSG. Proton magnetic resonance spectroscopy (1H-MRS) has been previously performed in Parkinson's disease (PD) to evaluate in vivo concentration of basal ganglia (BSG) and cerebral cortex metabolites. However this technique ...

OBJECTIVES This study aimed to investigate sympathetic nerve (SN) ultrastructural changes and hemodynamic and pulmonary artery (PA) pathological improvements by pulmonary arterial denervation (PADN) in animals with pulmonary arterial hypertension (PAH), as well as the underlying mechanisms. BACKGROUND SN overactivity plays a role in PAH. Previous studies have reported short-term improvements ...

CeO(2)-SnO(2) solid solution has been reported to possess high oxygen storage/release property which possibly originates from local structural distortion. We have performed first-principles based density functional calculations of Ce(1-x)Sn(x)O(2) structure (x=0, 0.25, 0.5, 1) to understand its structural stability in fluorite in comparison to rutile structure of the other end-member SnO(2), an...

Photometric and spectral evolution of the type Ic supernova SN 2007ru during the first 3 months are presented. The spectra show broad spectral features due to very high expansion velocity, normally seen in hypernovae. The photospheric velocity is higher than other type Ic supernovae. It is lower than SN 1998bw at ∼ 8 days after the explosion, but is comparable at later epochs. The light curve e...

We present spectroscopic VLT/UVES observations of two emerging supernovae, the Type Ia SN 2001el and the Type II SN 2003hn, in the spiral galaxy NGC 1448. Our high resolution and high signal-to-noise spectra display atomic lines of Ca , Na , Ti  and K  in the host galaxy. In the line of sight towards SN 2001el, we also detect over a dozen diffuse interstellar bands (DIBs) within NGC 1448....

BACKGROUND Numerous studies have demonstrated that patients with Parkinson's disease (PD) have a higher prevalence of substantia nigra (SN) hyperechogenicity compared with controls. Our aim was to explore the neuroimaging characteristics of transcranial sonography (TCS) of patients with PD and those with PD with dementia (PDD). The correlation between the echogenicity of the SN and clinical sym...

Diaminostannylenes react with [Ru(3)(CO)(12)] without cluster fragmentation to give carbonyl substitution products regardless of the steric demand of the diaminostannylene reagent. Thus, the Sn(3)Ru(3) clusters [Ru(3){μ-Sn(NCH(2)(t)Bu)(2)C(6)H(4)}(3)(CO)(9)] (4) and [Ru(3){μ-Sn(HMDS)(2)}(3)(CO)(9)] (6) [HMDS = N(SiMe(3))(2)] have been prepared in good yields by treating [Ru(3)(CO)(12)] with an ...

HIV-associated sensory peripheral neuropathy (HIV-SN) afflicts approximately 50% of patients on antiretroviral therapy, and is associated with significant neuropathic pain. Simple accurate diagnostic instruments are required for clinical research and daily practice in both high- and low-resource setting. A 4-item clinical tool (CHANT: Clinical HIV-associated Neuropathy Tool) assessing symptoms ...