We studied the dependence of the free thyroxin (T4) index and the ratio of T4 to thyroxin-binding globulin (TBG) on TBG concentrations, using sera from cases of congenital TBG deficiency and congenital TBG excess. Two such sera with similar concentrations of albumin, transthyretin, and free T4 were mixed to provide test samples with TBG concentrations covering the range of clinical interest wit...

We report an anesthetic experience in a clinically euthyroid patient with hyperthyroxinemia (elevated free thyroxine, fT4 and normal 3, 5, 3'-L-triiodothyronine, T3) and suspected impairment of conversion from T4 to T3. Despite marked hyperthyroxinemia, this patient's perioperative hemodynamic profile was suspected to be the result of hypothyroidism, in reference to the presence of T4 to T3 con...

Aim: To assess the effect of feeding live Saccharomyces cerevisiae on serum biochemistry in early weaned cross bred (Landrace × Desi) piglets Materials and Methods: 48 piglets assigned to four different groups (T1, T2, T3 and T4: n=12) following completely randomized design. T1 and T2 were weaned at age of 28 days while T3 and T4 were weaned at age of 42 days. T1 and T3 were fed basal diet with...

The aim of this stusy was to investigate whether spinal fusion to T2, T3, or T4 affects sagittal alignment of the cervical spine in Lenke 1 adolescent idiopathic scoliosis (AIS) patients.A retrospective study comprised of 64 Lenke 1 AIS patients was performed to assess the radiographic and clinical outcome. According to the upper instrumented vertebrae (UIV) (T2, T3, or T4), the patients were d...

BACKGROUND Recent studies have shown an association between thyroid hormone levels and metabolic syndrome (MetS) among euthyroid individuals; however, there have been some inconsistencies between studies. Here, we evaluated the relationship between thyroid hormone levels and MetS in euthyroid middle-aged subjects in a large cohort. METHODS A retrospective analysis of 13,496 euthyroid middle-a...

Abstract: The thyroid involvement is very significant feature of fluorosis due to fluoride accumulation in soft tissues. The participation of long term consumption of fluoride in drinking water on thyroid hormone status and deiodinating enzymes in fluorotic patients selected randomly from various parts of fluoride endemic areas, was elucidated. Type I (D1) activity was depressed significantly (...

The free concentration of bacteriophage T4-coded gene 32 (single-stranded DNA binding) protein in the cell is autoregulated a t the translational level during T4 infection of Escherichia coli. The control of the synthesis of this protein reflects the following progression of net (cooperative) binding affinities for the various potential nucleic acid binding targets present : single-stranded DNA...

Thyroxine-binding prealbumin (TBPA) in normal human serum has been shown in a polyacrylamide gel electrophoresis system to bind 7-9% of tracer level purified [(125)I]triiodothyronine (T3), and more than 30% of T3 in serum deficient in thyroxinebinding globulin (TBG). The T3-TBPA interaction has been confirmed at pH 9.0 and pH 7.4 in this electrophoretic demonstration of TBPA binding of T3 in se...

Like most phages with double-stranded DNA, phage T4 exits the infected host cell by a lytic process requiring, at a minimum, an endolysin and a holin. Unlike most phages, T4 can sense superinfection (which signals the depletion of uninfected host cells) and responds by delaying lysis and achieving an order-of-magnitude increase in burst size using a mechanism called lysis inhibition (LIN). T4 r...

The study was carried out to determine the effect of seasonal changes and oestrous cycle phase on serum progesterone (P4) and thyroxine (T4) profiles in Savanna Brown (SB) goats. Ten (n = 10) cycling SB goats with mean body weight and body mass index of 20.17 ± 0.2 kg and 6.2 ± 0.4, respectively were allotted to 2 groups of 5 animals each per season of study (Hot-rainy, HRS and cold-dry, CDR). ...