Independently folded domains in RNAs frequently adopt identical tertiary structures regardless of whether they are in isolation or are part of larger RNA molecules. This is exemplified by the P15 domain in the RNA subunit (RPR) of the universally conserved endoribonuclease P, which is involved in the processing of tRNA precursors. One of its domains, encompassing the P15 loop, binds to the 3'-e...

Background Magnetic resonance imaging (MRI) plays an essential role in molecular imaging by delivering the contrast agent into targeted cancer cells. The aim of this study was to evaluate the C595 monoclonal antibody-conjugated superparamagnetic iron oxide nanoparticles (SPIONs-C595) for the detection of breast cancer cell (MCF-7). Methods The conjugation of monoclonal antibody and nanopartic...

1. Stone2 has proved that a space is fully normal 7\ if and only if it is paracompact T2. If throughout his proof T\ is deleted and T2 is replaced by T4 (normality), we obtain that a space is fully normal if and only if it is paracompact TV In this note we prove that 7*2 can also be replaced by any one of the following: T2. Every two points with disjoint closures have disjoint neighborhoods. Ti...

This paper presents the new TNM classification in lung cancer and its history. Seventh edition of tumor, node, metastasis (TNM) classification in lung cancer has been published by the International Union Against Cancer (UICC) and the American Joint Committee on Cancer (AJCC) at the beginning of 2009. The changes were based upon the results of the international project of the International Assoc...

Background Osteoporosis affects 1 in 4 women and 1 in 8 men over 50 years and its burden on healthcare resources is enormous. Despite the risk factors and biological processes leading to bone loss have been well studied, little is known about the mechanisms that initiate bone loss in the first place. Osteocytes, marrow adipocytes and haematopoetic cell lines share a common precursor in the marr...

Many studies have been carried out with respect to packaging methods and temperature conditions of beef. However, the effects of packaging methods and temperature conditions on the quality characteristics have not been extensively studied in low-grade beef. Low-grade beef samples were divided into 3 groups (C: ziplock bag packaging, T1: vacuum packaging, and T2: modified atmosphere packaging (M...

PURPOSE To evaluate the biocompatibility and local sensibility reaction to bacterial cellulose hydrogel (0.8%) implanted in subcutaneous tissue of rabbits. METHODS Fifteen New Zeland rabbits were randomly allocated into three groups: T1, 7 days, T2, 21 days, and T3, 84 days. The new material was implanted in the subcutaneous tissue of the ear; on the scalp over the periosteum; and on the oute...

Introduction: Molecular oxygen (O2) is paramagnetic (χvol=1.8 ppm), and when present increases the magnetic susceptibility of lung gas. This effect has been demonstrated for investigation of pulmonary ventilation via the effective transverse relaxation time T2 of lung parenchyma [1]. In that method, T2 of the protons in lung tissue was mapped at baseline and after a few minutes of inhalation of...

The research work was planned on 120 unsexed day old broiler chicks, sixty each of Cari Vishal and Cobb broiler chicken to notice the effect on body weight gain and oocyst outputs against E. tenella infection. The effect of dosage of coccidial challenge was found to be significant (P<0.05) only at 4th week of age among treatment groups. The least squares mean (LSM) for body weight (g) differed ...

BACKGROUND The study was undertaken to determine whether a single slice magnetic resonance (MR) myelogram sequence improves the interpretation and diagnostic yield for magnetic resonance imaging (MRI) of the spine. METHODS A total of 100 cases with positive findings were retrospectively reviewed. All patients had initial imaging with sagittal T1-weighted (T1-W) and T2-weighted (T2-W) scans, f...