Background: Iron-mediated cardiomyopathy is the main complication of thalassemia major (TM) patients. Therefore, there is an important clinical need in the early diagnosis and risk stratification of patients. The aim of this study was to evaluate the efficacy of tissue doppler imaging (TDI) to study cardiac iron overload in patients with TM using T2* magnetic resonance (MR) as the gold-standard...

purpose t1wi (t1 weighted image) was acquired in order to grade bone fusion following the studies by fifa (federation internationale de football associations). research using images other than t1wi has not been reported. the aim of this study is to evaluate the grade of epiphyseal fusion by t2* weighted images (t2*wi) and to investigate new findings on t2*wi as compared with t1wi. methods a tot...

background: in recent years, the success in management of thalassemic patients, has allowed for some previously unrecognized complications including renal abnormalities to emerge. this prospective study aimed to investigate kidney iron overload by means of mri t2* and also renal function based on laboratory tests for early markers of glomerular and tubular dysfunction among adult iranian transf...

conclusion adrenal iron in β-tm can be reliably measured in 3 tesla mri. the results highlight the absence of correlation between adrenal iron deposition both with serum ferritin and hepatic iron. results among patients, there was no significant correlation between plasma ferritin and adrenal t2*. significant difference was detected among t2* values of adrenals between the patient and control g...

conclusion adc, fa, and t2* values may quantitatively reflect the microstructural characteristics of np, therefore they could be used to detect the minimal changes of early ldd. results the adc, fa, and t2* values were different (p < 0.05) among different rois within the same disc or among corresponding rois in different level discs. while the average values of adc increased regularly with the ...

the effect of ascorbic acid (aa) and butylated hydroxyanisole (bha) supplementation on aflatoxicosis in broiler chickens (1 to 42 days of age) was investigated (250, 500, 1000 and 2000 ppm for aa and bha) in diet containing 1 ppm total aflatoxin (af: 76.45% afb1, 10.52% afb2, 9.89% afg1 and 3.14% afg2). a total of 300 day-old broiler chicks were divided into ten treatment groups (t1=control; t2...