Objective: Apathy, a frequent neuropsychiatric symptom in aging neurocognitive disorders, has been associated with cognitive decline and functional disability. Therefore, timely provision of pharmacological interventions for apathy is greatly needed. Design: A systematical literature review existing studies was conducted up to 30 May 2023 several databases (PubMed, PsychInfo, Cochrane, Google S...

Nat-siRNAs (small interfering RNAs originated from natural antisense transcripts) are a class of functional small RNA (sRNA) species discovered in both plants and animals. These siRNAs are highly enriched within the annealed regions of the NAT (natural antisense transcript) pairs. To date, great research efforts have been taken for systematical identification of the NATs in various organisms. H...

We consider the physics potential of CERN based neutrino oscillation experiments consisting of a Beta Beam (βB) and a Super Beam (SPL) sending neutrinos to MEM-PHYS, a 440 kt wateř Cerenkov detector at Fréjus, at a distance of 130 km from CERN. The θ 13 discovery reach and the sensitivity to CP violation are investigated, including a detailed discussion of parameter degeneracies and systematica...

In many systems, the time scales of the microscopic dynamics and macroscopic dynamics of interest are separated by many orders of magnitude. Examples abound, for instance, nucleation, protein folding, and chemical reactions. For these systems, direct simulation of phase space trajectories does not efficiently determine most physical quantities of interest. The past decade has seen the advent of...

Parallel programming using the current state-of-the-art in software engineering techniques is hard. Expertise in parallel programming is necessary to deliver good performance in applications; however, it is very common that domain experts lack the requisite expertise in parallel programming. In order to drive the computer science research toward effectively using the available parallel hardware...

Gallium exhibits weak metallic properties owing to its proximity non-metals in the periodic table, yet is volatile extra-terrestrial bodies and fairly reactive nature. It has been used extensively elucidate Solar System evolution, planet interior differentiation, terrestrial processes. However, Ga speciation transformation various planetary compartments dynamics of trans-reservoir pathways rema...

Automated construction of deep neural networks (DNNs) has become a research hot spot nowadays because DNN’s performance is heavily influenced by its architecture and parameters, which are highly task-dependent, but it notoriously difficult to find the most appropriate DNN in terms parameters best solve given task. In this work, we provide an insight into automated process formulating multilevel...