Irritable bowel syndrome (IBS) is a chronic condition that affects 11.2% of the world’s population. The management gut microbiota using probiotic and synbiotic agents might be valid alternative to assist in treatment IBS. focus this study was evaluate effects prebiotic compounds carried by different foods on major symptoms IBS through systematic literature review. MEDLINE, EMBASE, Cochrane Cent...

Abstract Beneficial effects of Bifidobacterium spp. on gut microbiota development and infant health have been reported earlier. Therefore, supplementation formulas with probiotic bifidobacteria, as well prebiotics stimulating bifidobacterial growth, has proposed. Here, we studied the faecal microbiome infants supplemented specialized nutrition, which some received a standard amino acid-based fo...

The study was performed to investigate the effect of combinations of feed additives consisting of either a combination of a probiotic and a prebiotic (synbiotic), or a combination of a probiotic and xylanase on ileal nutrient digestibility, ileal microbial metabolite concentrations, and microbial composition in ileal digesta of weaned piglets. In total, 12 six-week old barrows with an average i...

We tested the association between aberrant crypt foci (ACF) and tumor induction by feeding azoxymethane-induced rats (15 mg/kg x 2, s.c.) with synbiotics (Raftilose Synergy 1, a derivative of inulin, 10% of the diet, along with lactobacilli and bifidobacteria). After 16 weeks of feeding, synbiotics significantly increased ACF multiplicity. On the contrary, after 32 weeks, synbiotics significant...

Increased susceptibility of birds to avian pathogens in intensive husbandry system has emphasized on necessity of improvement of innate and specific immune responses of birds by the fast establishment of a beneficial microflora and immune stimulator factors to guarantee healthy and low-price products. During this study, 192 one-day-old broiler chicks (Ross-380) in four groups with three replica...

PURPOSE Breastfeeding is the best way to feed all infants, but not all infants can be (exclusively) breastfed. Cow's milk based infant formula is the second choice infant feeding. METHODS The safety of a new synbiotic infant formula, supplemented with Bifidobacterium lactis and fructo-oligosaccharides, with lactose and a whey/casein 60/40 protein ratio was tested in 280 infants during 3 month...

Michael T. Cook, George Tzortzis, Dimitris Charalampopoulos*, Vitaliy V. Khutoryanskiy* 4 School of Pharmacy, University of Reading, Reading, RG6 6AD, United Kingdom 5 Clasado Research Services Ltd, Science and Technology Centre, University of Reading, Earley 6 Gate, Whiteknights Road, Reading, RG6 6BZ, United Kingdom 7 Department of Food and Nutritional Sciences, University of Reading, Reading...

An in vivo experiment was conducted to study the effects of probiotic Bacillus coagulans spores, with and without prebiotic, inulin, on gastrointestinal (GI) microbiota of healthy rats and its potentiality to survive in the GI tract. Forty-eight male Wistar rats were randomly divided into four groups (n=12) and fed as follows: standard diet (control), standard diet supplied with 5% w/w long cha...

Here, the olive leaf extract (OLE) rich in polyphenols was employed as a prebiotic agent, together with Lactobacillus reuteri and Bacillus clausii, to develop synbiotics. The effect of on probiotic strains tested at concentrations 0, 50, 100, 400, 1000 μg mL−1, also 20 40 mg mL−1. Olive mL−1 showed best activity L. B. clausii. A basal diet two experimental synbiotic-containing diets were prepar...