BACKGROUND The relationship between occupational exposure to magnetic fields and brain cancer in men was investigated using population-based case-control data collected in eight Canadian provinces. Emphasis was placed on examining the variations in risk across different histological types. METHODS A list of occupations was compiled for 543 cases and 543 controls that were individually matched...

1 Penn State Institute of the Neurosciences and Penn State Cancer Institute, Hershey, PA 17033, USA 2The Ohio State University College of Medicine, Columbus, OH 43210, USA 3Departments of Health Evaluation Sciences and Neurosurgery, Penn State College of Medicine/Penn State Milton S. Hershey Medical Center, Hershey, PA 17033, USA 4Radiation Oncology Brain Tumor Laboratory, University of Alabama...

Successful oncolytic virus treatment of malignant glioblastoma multiforme depends on widespread tumor-specific lytic virus replication and escape from mitigating innate immune responses to infection. Here we characterize a new HSV vector, JD0G, that is deleted for ICP0 and the joint sequences separating the unique long and short elements of the viral genome. We observed that JD0G replication wa...

based on the problems caused by today conventional vehicles, much attention has been put on the fuel cell vehicles researches. however, using a fuel cell system is not adequate alone in transportation applications, because the load power profile includes transient that is not compatible with the fuel cell dynamic. to resolve this problem, hybridization of the fuel cell and energy storage device...

BACKGROUND AND PURPOSE Pre-treatment ADC characteristics have been shown to predict response to bevacizumab in recurrent glioblastoma multiforme. However, no studies have examined whether ADC characteristics are specific to this particular treatment. The purpose of the current study was to determine whether ADC histogram analysis is a bevacizumab-specific or treatment-independent biomarker of t...

BACKGROUND Despite improvements in surgical technique, radiation therapy delivery, and options for systemic cytotoxic therapy, the median survival for patients with newly diagnosed glioblastoma multiforme remains poor at 15 months with trimodality therapy. Multiple immunologic approaches are being tested to enhance the response of these tumors to existing therapy and/or to stimulate innate immu...