background: omega-3 polyunsaturated fatty acids (pufa) have beneficial effects on both specific and non-specific inflammatory reactions. the aim of this study was to evaluate the effect of dietary supplementation with fish oil in migraine prevention. methods: a 12-week, randomized, single-blind clinical trial was conducted from october 2008 to june 2009. a total of 67 patients (52 women, 15 men...

BACKGROUND High oxidative stress and chronic inflammation can contribute to the pathogenesis of coronary artery disease (CAD). Coenzyme Q10 is an endogenous lipid-soluble antioxidant. Statins therapy can reduce the biosynthesis of coenzyme Q10. The purpose of this study was to investigate the effects of a coenzyme Q10 supplement (300 mg/d; 150 mg/b.i.d) on antioxidation and anti-inflammation in...

Stroke remains the number one cause of disability in the adult population. Despite scientific progress in our understanding of stroke pathology, only one treatment (tissue plasminogen activator or tPA) is able to afford benefits but to less than 3% of ischemic stroke patients. The development of experimental dietary supplement therapeutics designed to stimulate endogenous mechanisms that confer...

OBJECTIVES Glutamine is an important fuel for intestinal mucosal epithelial cells, and it promotes intestinal mucosal cell differentiation and proliferation. Most liver transplantation (LT) patients suffer from intestinal barrier dysfunction. Whether enteral glutamine supplementation has beneficial effects on intestinal barrier function following LT is not known. We investigated the effect of g...

INTRODUCTION N-3 Polyunsaturated fatty acids (n-3 PUFA) exert clinical beneficial effects in patients after acute myocardial infarction (AMI). However, their exact mechanisms of action are not well recognized yet. Our aim was to evaluate effects of early introduced n-3 PUFA supplementation on endothelial function and serum adipokine concentrations in patients with AMI. MATERIAL AND METHODS Th...

Inhaled bronchodilators and corticosteroids, when indicated, form the backbone of COPD therapy. However, over last decade there has been an emergence adjunct therapies in oral or inhaled that are now part therapeutic approach to COPD. While these have shown be beneficial used appropriate instances, particular considerations need minded using therapies. This review article discussed mechanism ro...

Pancreatic insufficient children with cystic fibrosis (CF) are routinely supplemented fat-soluble vitamins A, D, E, and K, serum vitamin levels checked in annual review assessments. Prior to 2018, the formulations involved preparations that provide Vitamin K separately, but A D together. This has proven be challenging for parents carers looking after young CF. Anew formulation (Paravit – CF), c...

AIM To evaluate the efficacy of water supplementation treatment in patients with functional dyspepsia or irritable bowel syndrome (IBS) accompanying predominant constipation. METHODS A total of 3872 patients with functional dyspepsia and 3609 patients with irritable bowel syndrome were enrolled in the study by 18 Italina thermal centres. Patients underwent a first cycle of thermal therapy for...