three levels of lysine (90, 100 and 110% of ross requirement) and of pyridoxine (3, 6 and 9 mg kg-1) were used in a 3 × 3 factorial experiment to investigate the growth and blood antioxidant ability of broilers under high ambient temperature. none of the dietary supplements affected the weight gain during the starter and grower periods. although no significant differences were detected between ...

BACKGROUND CuZn-Superoxide dismutase (SOD) is a unique enzyme, which can catalyzes the dismutation of inevitable metabolic product i.e.; superoxide anion into molecular oxygen and hydrogen peroxide. The enzyme has gained wide interest in pharmaceutical industries due to its highly acclaimed antioxidative properties. The recombinant expression of this protein in its enzymatically active and stab...

Superoxide dismutase has been studied in a wide range of organisms (Fridovich, 1975). Early observations suggested that superoxide dismutases isolated from eukaryotes (McCord & Fridovich, 1969; Misra & Fridovich, 1972; Beauchamp & Fridovich, 1973) showed little diversity in their properties, having mol.wts. near 32000 and containing two copper and two zinc atoms per molecule. The activity of th...

Investigaltions to determine the effect of sample storage on the concentration of copper in liver tissue and on the activity of erythrocyte superoxide dismutase were undertaken in preparation for a study of blesbok (Damaliscus pygargus phillipsi) that were suspected to be suffering from copper deficiency. Two liver samples were collected from each of 20 culled blesbok in a manner that simulated...

SOD2 encodes manganese superoxide dismutase, a mitochondrial enzyme that protects the cell against damage from superoxide free radicals. A common polymorphism, a T ! C transition (Val16Ala), was shown to alter the manganese superoxide dismutase mitochondrial targeting sequence (1). Animal studies have linked reduction in manganese superoxide dismutase activity to increased DNA damage and higher...

An antimicrobial system has been previously described in the polymorphonuclear leukocyte which consists of myeloperoxidase, H202, and a halide. In the present study, H202 is replaced by xanthine and xanthine oxidase in the isolated myeloperoxidase-mediated antimicrobial system and the contribution of the superoxide anion (02T) and hydroxyl radicals (*OH) to the antimicrobial effect investigated...