In this work a novel bioassay for mustard agent detection was proposed. The bioassay is based on the capability of these compounds to inhibit the enzyme choline oxidase. The enzymatic activity, which is correlated to the mustard agents, was electrochemically monitored measuring the enzymatic product, hydrogen peroxide, by means of a screen-printed electrode modified with Prussian Blue nanoparti...

introduction: sulfur mustard (sm), a toxic alkylating gas, can cause serious long-term pulmonary complications such as chronic obstructive pulmonary disease (copd). metabolic syndrome (mets) is one of the important comorbidities of copd. this study was designed to evaluate the frequency of metabolic syndrome in iranian chemical warfare patients (cwps) with copd. materials and methods: thirty cw...

background: sulfur mustard (sm) as a chemical warfare agent, increases permeability of bronchial vessels and damages airway epithelium. sm exposure causes debilitating respiratory complications. this study was designed to evaluate clinical respiratory manifestations, and to compare chest x ray (cxr) and high resolution computed tomography (hrct) scan of chest in sm exposed patients with respira...

sulfur mustard (sm, bis- (2-chloroethyl) sulphide) is a chemical warfare agent that causes dna alkylation, protein modification and membrane damage. sm can trigger several molecular pathways involved in inflammation and oxidative stress, which cause cell necrosis and apoptosis, and loss of cells integrity and function. epigenetic regulation of gene expression is a growing research topic and is ...

In the last few years many chemically injured patients have been visited throughout the country in order to investigate the late respiratory complications of sulfur mustard. 35 patients who were previously admitted for mustard poisoning underwent complete clinical examination as well as spirometry, fiberoptic bronchoscopy (FOB), Bronchoalveolar lavage (BAL), and trans bronchial lung biopsy...

PURPOSE The purpose of this study was to evaluate the relationship between volatile sulfur compounds (VSC) and gingival health status and to determine if volatile sulfur compounds can detect early dental plaque-induced gingival disease. METHODS A split-mouth design with randomly selected quadrants of the mandibular arch enabled 39 participants to serve as their own controls. At baseline and a...

I. A large body of evidence has been accumulated in recent years which indicates that proteins have very large molecular weights. The molecular weight of egg albumin, the smallest of the proteins that have been adequately studied, is approximately 34,000. This estimate was made by S0rensen14 on the basis of osmotic pressure measurements in which he corrected for the unavoidable influence of ino...

O6-Ethylthioethyldeoxyguanosine has been synthesized from 6-chloro-3',5'-di-O-acetyldeoxyguanosine and characterized by UV, fluorescence, and mass spectrometry. High-pressure liquid chromatography studies have shown that this modified nucleoside is formed when the one-armed sulfur mustard, chloroethyl ethyl sulfide, reacts with deoxyguanosine. This result supports the hypothesis that the mutage...

The old Japanese army developed several chemical warfare agents on Ohkuno Island in Seto inland sea, Hiroshima Japan, during the period between 1919 and 1944. These chemical agents including yperite (mustard; irritating agent), lewisite (irritating agent), diphenylchloroarsine (DA; vomiting agent), diphenylcyanoarsine (DC; vomiting agent) and other poisonous gases were manufactured to be used i...