The present study was designed to investigate the hypothesis that in vivo entosis is a novel pathway for eliminating spermatozoa in the seminiferous tubules (ST) during hibernation of the Chinese soft-shelled turtle. Western blot analysis revealed that the expression of LAMP1 in the testis was significantly higher during hibernation than that during non-hibernation. Immunohistochemistry reactio...

Hibernating mammals conserve energy in the winter by undergoing prolonged bouts of torpor, interspersed with brief arousals back to euthermia. These bouts are accompanied by a suite of reversible physiological and biochemical changes; however, much remains to be discovered about the molecular mechanisms involved. Given the seasonal nature of hibernation, it stands to reason that underlying plas...

Myostatin, a negative regulator of muscle mass, is elevated during disuse and starvation. Mammalian hibernation presents a unique scenario, where animals are hypocaloric and in torpor, but the extent of muscle protein loss is minimized. We hypothesized that myostatin expression, which is usually increased early in disuse and under hypocaloric conditions, could be suppressed in this unique model...

TSVETKOV, Ts., Ts. TAKEVA and A. SOLAK, 2006. To the problem of experimental hibernation I. About the role of endogenous hibernation trigger. Bulg. J. Agric. Sci., 1-5 Experimented 24 white mice (Mus Musculus), divided into 2 groups of twelve. The fist 12 animals have been injected intraperitoneal (i.p.) with blood plasma (in different doses) from ground squirrels by the time of deep hibernatio...

During autumn in the temperate zone of both the new and old world, bats of many species assemble at underground sites in a behaviour known as swarming. Autumn swarming behaviour is thought to primarily serve as a promiscuous mating system, but may also be related to the localization and assessment of hibernacula. Bats subsequently make use of the same underground sites during winter hibernation...

An important disease among human metabolic disorders is type 2 diabetes mellitus. This disorder involves multiple physiological defects that result from high blood glucose content and eventually lead to the onset of insulin resistance. The combination of insulin resistance, increased glucose production, and decreased insulin secretion creates a diabetic metabolic environment that leads to a lif...

WANG, LAWRENCE C. H. Radiotelemetric study of hibernation under natural and laboratory conditions. Am. J. Physiol. 224(3): 673-677. 1973.-The body temperature of hibernating Richardson’s ground squirrel (Spermophilus richardsom) was measured by radiotelemetry both in its natural habitat and in the laboratory. Under natural conditions, hibernation extended from mid-September to early March. The ...