نتایج جستجو برای: subunit g

تعداد نتایج: 521741  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2013
Feng Li Samsudeen Ponissery-Saidu Karen K Yee Hong Wang Meng-Ling Chen Naoko Iguchi Genhua Zhang Ping Jiang Johannes Reisert Liquan Huang

The activation of G-protein-coupled olfactory receptors on the olfactory sensory neurons (OSNs) triggers a signaling cascade, which is mediated by a heterotrimeric G-protein consisting of α, β, and γ subunits. Although its α subunit, Gαolf, has been identified and well characterized, the identities of its β and γ subunits and their function in olfactory signal transduction, however, have not be...

2011
Michael T. Morgan Atanu Maiti Megan E. Fitzgerald Alexander C. Drohat

Deamination of 5-methylcytosine to thymine creates mutagenic G · T mispairs, contributing to cancer and genetic disease. Thymine DNA glycosylase (TDG) removes thymine from these G · T lesions, and follow-on base excision repair yields a G · C pair. A previous crystal structure revealed TDG (catalytic domain) bound to abasic DNA product in a 2:1 complex, one subunit at the abasic site and the ot...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2003
Amy Benians Joanne L Leaney Andrew Tinker

G protein-gated inwardly rectifying K(+) (Kir) channels are found in neurones, atrial myocytes, and endocrine cells and are involved in generating late inhibitory postsynaptic potentials, slowing the heart rate and inhibiting hormone release. They are activated by G protein-coupled receptors (GPCRs) via the inhibitory family of G protein, G(i/o), in a membrane-delimited fashion by the direct bi...

Journal: :Genes & development 1993
P Lilly L Wu D L Welker P N Devreotes

Recent studies have demonstrated that G-protein-linked signal transduction pathways play a significant role in the developmental program of the simple eukaryotic organism Dictyostelium. We have reported previously the isolation of a G-protein beta-subunit and present here a more complete analysis of this gene. Low-stringency Southern blots and RFLP mapping studies suggest that the beta-subunit ...

Journal: :The American journal of occupational therapy : official publication of the American Occupational Therapy Association 2007
Heather Miller-Kuhaneck Diana A Henry Tara J Glennon Keli Mu

OBJECTIVE The history and development of the Sensory Processing Measure-School are detailed, and findings of initial pilot studies are reported. METHOD Multiple reviews, focus groups, case studies, and two pilot studies were used to develop the early versions of the tool. Internal consistency and discriminatory ability were examined. RESULTS Internal consistency measured with Cronbach's alp...

2015
Xiao-you Su Joseph TF Lau Winnie WS Mak KC Choi Tie-jian Feng Xi Chen Chu-liang Liu Jun Liu De Liu Lin Chen Jun-min Song Yan Zhang Guang-lu Zhao Zhang-ping Zhu Jin-quan Cheng

BACKGROUND The Brief COPE instrument has been utilized to conduct research on various populations, including people living with HIV (PLWH). However, the questionnaire constructs when applied to PLWH have not been subjected to thorough factor validation. METHODS A total of 258 PLWH were recruited from two provinces of China. They answered questions involving the scales of three instruments: th...

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