BACKGROUND Exertional fatigue, which frequently limits exercise in patients with chronic heart failure, is associated with early anaerobic metabolism in skeletal muscle. The present study was designed to examine the skeletal muscle metabolic response to exercise in this disorder and determine the relation of reduced muscle blood flow and skeletal muscle biochemistry and histology to the early o...

background: regular aerobic exercise improves the background: regular aerobic exercise improves the inflammatory status in different lung diseases. however, the effects of long-term aerobic exercise on the lung response have not been investigated. the present study evaluated the effect of aerobic exercise on the lung inflammatory. m aterials and methods: 12 adult male wistar rats were divided t...

BACKGROUND Patients with myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) are unable to activate brain-orchestrated endogenous analgesia (or descending inhibition) in response to exercise. This physiological impairment is currently regarded as one factor explaining post-exertional malaise in these patients. Autonomic dysfunction is also a feature of ME/CFS. OBJECTIVES This study ...

Purpose to examine the effect of a 4-day NO3- loading protocol on the submaximal oxygen cost of both low fit and high fit participants at five different exercise intensities. Methods participants were initially assigned to a placebo (PL; negligible NO3-) or inorganic nitrate-rich (NR; 6.2 mmol nitrate/day) group; double-blind, placebo-controlled, crossover. Participants completed three trials...

In a randomized, double-blind crossover design, we investigated the effect of the beta2-agonist terbutaline (TER) on endurance performance and substrate utilization in nine moderately trained men [maximum oxygen uptake (V̇O(2 max)) 58.9 ± 3.1 ml·min(-1)·kg(-1)]. Subjects performed 60 min of submaximal exercise (65-70% of V̇O(2 max)) immediately followed by a 300-kcal time trial with inhalation of...

background there is a strong relationship between physical inactivity and low-grade inflammation and its adverse health outcomes, particularly cardiovascular disease. the level of anti-inflammatory and pro-inflammatory cytokines may be changed by exercise. objectives the aim of the present study was to determine the response of certain inflammatory biomarkers to exercise with differences in max...

There are several marked adaptations associated with the regular performance of endurance training. Aerobic endurance training produces increases in VO2 max (13, 7, 8), but has no hypertrophy effect on muscle (6). Muscle fibre size has actually been shown to decrease (15, 11). Capillary supply to the muscles has been shown to change in response to endurance training through an increase in the c...

INTRODUCTION Single acute bouts of moderately-intense aerobic exercise like walking have been found to improve cognitive control of attention in children, but some studies have reported no improvement in cognitive flexibility following acute aerobic exercise. Submaximal aerobic exercise performed for 60 minutes facilitated specific aspects of information processing in adults but extended exerci...

Background. Beetroot consumption has been proposed to improve exercise performance, since the nitrate content of this food is able to stimulate the synthesis of nitric oxide. Objective. The acute effect of 100 g of a beetroot gel containing ~10 mmol of nitrate was tested on the nitric oxide synthesis, on metabolic and biochemical parameters, and on performance in physically active individuals. ...