OBJECTIVE To determine the effects of topical application of capsaicin on cutaneous autonomic nerves. METHODS Thirty-two healthy subjects underwent occlusive application of 0.1% capsaicin cream (or placebo) for 48 hours. Subjects were followed for 6 months with serial assessments of sudomotor, vasomotor, pilomotor, and sensory function with simultaneous assessment of innervation through skin ...

Topical Bimatoprost is a common and popular prostaglandin analog used as an ocular hypotensive agent in the treatment of glaucoma. Side effects include ocular hyperaemia, ocular pruritus, and periocular and iris pigmentary changes. Perioribital lipodystrophy is another well-documented outcome associated with chronic use of topical bimatoprost, which results in periorbital hallowing, upper eyeli...

Topical preparations are dosage forms applied to the skin for local therapy. These topical contain several types of bases that used drug formulations. This review aimed determine type base is effective and widely in basil leaf function as antioxidants, antibacterial agents, wound healing. The research method comparative, namely, reviewing articles on formulations products with various concentra...

We propose an adaptive reversible data hiding method with superior visual quality and capacity in which an adaptive generalized difference expansion (AGDE) method is applied to an integer-to-integer subband transform (I2I-ST). I2I-ST performs the reversible subband transform and the AGDE method is a state-of-the-art method of reversible data hiding. The results of experiments we performed objec...

joint pain is one of the most common complaints with many possible causes.some medicines used for joint pain relief such as nsaids have substantial and frequent side effects. topical route possibly reduces adverse reactions by maximizing local delivery and minimizing systemic toxicity. throughout history, plants have been the most important sources of medicines for human health and iranian trad...