derivative of tanshinone IIa, which is the main lipophilic component contained in Salvia miltiorrhiza known as ‘Danshen’ in traditional Chinese medicine. The pharmacological activity of STS is due to tanshinone IIA, which is a cardioprotective substance and may exert a beneficial effect on the clinically important vascular endothelium. The use of tanshinone IIA is limited by its poor water solu...

Much is known about the sit-to-stand (STS) and its biomechanics. Currently, however, there is little opportunity for instrumented quantification of the STS as part of screening or diagnosis in clinical practice. The objectives of the present study were to describe the feasibility of using an automated approach for quantifying the STS using one sensor location and to start testing the discrimina...

STS (soft tissue sarcomas) are rare malignant tumours deriving from cells of mesenchymal origin and represent only 1% of all malignant neoplasms. It has been extensively demonstrated that angiogenesis has an important role in cancer malignancy. Particularly, a lot of studies demonstrate the importance of angiogenesis in the development of carcinomas, whereas little is known about the role of an...

Sodium tanshinone IIA sulfonate (STS) is a derivate of tanshinone IIA, a lipophilic compound in Salvia miltiorrhiza. This study aimed to investigate the effect of STS on ion transport in mouse tracheal epithelium and the mechanisms underlying it. Short-circuit current (Isc) was measured to evaluate the effect of STS on transepithelial ion transport. Intracellular Ca2+ imaging was performed to o...

The ability to perform a sit-to-stand (STS) motion is important for ambulatory adults to function independently and maintain daily activities. Roughly 6% of community-dwelling older adults experience significant difficulties with STS, a major risk factor for institutionalization. While mechanical STS assistance can help address this problem, full dependence on STS assistance provided by devices...

In this paper, an electron transfer reaction mediated by sodium tanshinone IIA sulfonate (STS) was studied in rat heart mitochondria. It was found that STS could stimulate mitochondrial NADH oxidation dose-dependently and partly restore NADH oxidation in the presence of respiratory inhibitor (rotenone or antimycin A or KCN). It was likely that STS could accept electrons from complex I similar t...

Sit-to-stand (STS) motions are one of the most important activities of daily living as they serve as a precursor to mobility and walking. However, there exist no standard method of segmenting STS motions. This is partially due to the variety of different sensors and modalities used to study the STS motion such as force plate, vision, and accelerometers, each providing different types of data, a...

[Purpose] The purpose of this study was to compare the activation of the gluteus medius (Gmed), rectus femoris (RF), and biceps femoris (BF) muscles during neutral (N) sit to stand (STS) and STS involving hip abduction (ABD) in elderly females. [Subjects] We recruited 16 healthy elderly females with no pain in the knee joint or any other orthopedic problems of the lower limbs. [Methods] The act...

Properties of the 11 084 874 829 Steiner triple systems of order 19 are examined. In particular, there is exactly one 5-sparse, but no 6-sparse, STS(19); there is exactly one uniform STS(19); there are exactly two STS(19) with no almost parallel classes; all STS(19) have chromatic number 3; all have chromatic index 10, except for 4 075 designs with chromatic index 11 and two with chromatic inde...

BACKGROUND The ability to rise from sitting to standing is critical to an individual's quality of life, as it is a prerequisite for functional independence. The purpose of the current study was to examine the hypothesis that test durations as assessed with the instrumented repeated Sit-To-Stand (STS) show stronger associations with health status, functional status and daily physical activity of...