نتایج جستجو برای: structural dependent biological activity
تعداد نتایج: 2375451 فیلتر نتایج به سال:
Cyanobacteria produce a variety of chemically diverse cyclic lipopeptides with potent antifungal activities. These have an amphipathic structure comprised polar peptide cycle and hydrophobic fatty acid side chain. Many antibiotic activity against range human plant fungal pathogens. This review article aims to summarize the present knowledge on chemical diversity cellular effects cyanobacterial ...
Three sulphated polysaccharides labelled at the reducing end with three different chemical treatments [2-aminopyridine (2-AP), 8-amino-1,3,6-trisulphonic acid (ANTS) and 6-(biotinyl)-aminocaproylhydrazide (BACH)] were compared. Molecular weight, chemical composition, nuclear magnetic resonance features and anticoagulant activity expressed as activated partial thromboplastin time were studied to...
Terpenes from marine-derived fungi show a pronounced degree of structural diversity, and due to their interesting biological and pharmacological properties many of them have aroused interest from synthetic chemists and the pharmaceutical industry alike. The aim of this paper is to give an overview of the structural diversity of terpenes from marine-derived fungi, highlighting individual example...
This paper investigates the uncertainty-dependent and sign-dependent effects of oil market fundamental shocks, namely supply, aggregate demand oil-specific shocks. We do so by first proposing a novel uncertainty index that is measured stochastic volatility unpredictable component prices. then employ nonlinear model find all reactions production, real price oil, global economic activity to struc...
Site-directed mutagenesis previously identified the residues responsible for the biological activity of the plant defense legume lectin, Griffonia simplicifolia lectin II (GSII) [Proc. Natl. Acad. Sci. USA 95, (1998) 15123-15128]. However, these results were inconclusive as to whether these residues function as direct defense determinants through carbohydrate binding, or whether substantial cha...
Activity-dependent rapid structural and functional modifications of central excitatory synapses contribute to synapse maturation, experience-dependent plasticity, and learning and memory and are associated with neurodevelopmental and psychiatric disorders. However, the signal transduction mechanisms that link glutamate receptor activation to intracellular effectors that accomplish structural an...
Non-enzymic binding of sugars to proteins (glycation) is a common biological phenomenon that is increased in diabetes. Most work has been directed towards structural proteins which may be present for many years and would continue to accumulate sugar residues. As glycation is a non-specific reaction, other proteins such as enzymes will also be susceptible to glycation and could well display alte...
BRCC36 is a Zn(2+)-dependent deubiquitinating enzyme (DUB) that hydrolyzes lysine-63-linked ubiquitin chains as part of distinct macromolecular complexes that participate in either interferon signaling or DNA-damage recognition. The MPN(+) domain protein BRCC36 associates with pseudo DUB MPN(-) proteins KIAA0157 or Abraxas, which are essential for BRCC36 enzymatic activity. To understand the ba...
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