To test whether hypertension can cause hyperinsulinemia or insulin resistance, we performed intravenous glucose tolerance tests at 1 month and euglycemic clamps at 3 months after induction of two-kidney, one clip renovascular hypertension in rats. At 1 month, systolic pressure was higher in 21 clipped than in 12 control animals (161 +/- 5 mm Hg, range 134-187 mm Hg versus 119 +/- 3 mm Hg, range...

INTRODUCTION The aim of this study was to evaluate beta-cell function and insulin resistance in relation to the occurrence of anti-islet antibodies in first degree relatives of patients with type 1 diabetes (T1D). MATERIAL AND METHODS The group studied consisted of 90 relatives and 60 healthy individuals without a family history of diabetes. An intravenous glucose tolerance test (IVGTT) was p...

A novel gibberellin (GA)-deficient mutant designated dwarf and delayed-flowering 1 (ddf1) was isolated from a library of activation-tagged Arabidopsis. This mutant showed dwarfism and late-flowering, but the phenotype was rescued by exogenous GA3 like known mutants defective in GA biosynthesis. The contents of bioactive GA4 and GA1 were in fact decreased in ddf1 at least partially through the r...

The submodules with the property of the title ( a submodule $N$ of an $R$-module $M$ is called strongly dense in $M$, denoted by $Nleq_{sd}M$, if for any index set $I$, $prod _{I}Nleq_{d}prod _{I}M$) are introduced and fully investigated. It is shown that for each submodule $N$ of $M$ there exists the smallest subset $D'subseteq M$ such that $N+D'$ is a strongly dense submodule of $M$ and $D'bi...

AIMS To investigate whether admission hyperglycaemia in non-diabetic patients with acute myocardial infarction (AMI) is a surrogate for previously undiagnosed abnormal glucose tolerance. METHODS AND RESULTS Two hundred non-diabetic patients with AMI were divided into three groups: 81 patients with admission glucose < 7.8 mmol/L (group 1), 83 patients with admission glucose > or = 7.8 mmol/L a...

in this paper, we introduce the dual notion of strongly top modules and study some of the basic properties of this class of modules.

Abstract Twenty years ago, the UN adopted a zero-tolerance policy on sexual exploitation and abuse (SEA) by its personnel. After prohibiting sex with children exchange of for “cash, food things,” it “strongly discourages” relationships beneficiaries because “they are based inherently unequal power dynamics” undermine UN’s credibility integrity. Taking inspiration from critical feminist project ...

Animal personalities are common across taxa and have important evolutionary and ecological implications. Such consistent individual differences correlate with important life-history traits such as dispersal. Indeed, some environmental conditions are supposed to determine dispersers with a specific personality. For example, an increased density should promote the departure of individuals with le...

The effect of exposure of Aedes aegypti larvae for 72h to sub-lethal concentrations of the herbicide glyphosate and the polycyclic aromatic hydrocarbon benzo[a]pyrene on their subsequent tolerance to the chemical insecticides imidacloprid, permethrin and propoxur, detoxification enzyme activities and transcription of detoxification genes was investigated. Bioassays revealed a significant increa...