—The U.S. Department of Agriculture’s National Center for Cool and Cold Water Aquaculture is conducting a breeding program for rainbow trout Oncorhynchus mykiss to develop improved germplasm for the U.S. aquaculture industry. Current selection efforts are focused on growth and disease resistance, but stress response is also a concern. Using plasma cortisol concentrations after a 3-h crowding st...

Endoplasmic reticulum stress has been linked to insulin resistance in multiple tissues but the role of endoplasmic reticulum stress in skeletal muscle has not been explored. Endoplasmic reticulum stress has been reported to increase tribbles 3 expression in multiple cell lines. Here, we report that high-fat feeding in mice, and obesity and type 2 diabetes in humans significantly increases tribb...

Anxiety disorders are the most common reasons for referring to specialized clinics. If the response to stress changed, anxiety can be greatly controlled. The most obvious effect of stress occurs on circulatory system especially through sweating. the electrical conductivity of skin or in other words Galvanic Skin Response (GSR) which is dependent on stress level is used; beside this parameter pe...

crisis due to global warming and its associated damaging consequences, including salinity, it is essential to develop plant resistance to salinity level. in this study, an experiment was conducted using different levels of salinity (0.05, 0.1, 0.15 and 0.2% sodium chloride) had on rosa hybrida, as the most important cut flowers in the world. results showed that by increasing of salinity, sodium...

OBJECTIVE Pathology associated with oxidative stress frequently results in insulin resistance. Glutathione (GSH) and GSH-linked metabolism is a primary defense against oxidative stress. Electrophilic lipid alkenals, such as 4-hydroxy-t-2-nonenal (4HNE), generated during oxidative stress are metabolized primarily to glutathione electrophile (GS-E) conjugates. Recent studies show that RLIP76 is t...

Hypertension, insulin resistance, and obesity are common age-related metabolic disorders that are often associated with increased oxidative stress and the resultant vascular damage. Underlying mechanisms have been suggested, and age-related overproduction of oxidative stress is one possible candidate. Since we recently found a vasoactive peptide, adrenomedullin, to be an endogenous antioxidant ...

Mutations that extend nematode longevity by interference with IGF-I/insulin sensing pathways also lead to resistance to multiple forms of stress. Here, we report that skin-derived fibroblasts from Snell dwarf mice, already known to show increased longevity and delayed aspects of aging, are resistant to multiple forms of cellular stress, including UV light, heat, paraquat, H2O2, and the toxic me...