iabetes mellitus (DM) is a major risk factor among typical coronary risk factors that must be considered in the primary and secondary prevention of coronary artery disease (CAD).1–3 The prognosis of diabetic patients without known CAD is reportedly similar to those with previous myocardial infarction.4,5 The diagnostic limitation for CAD in this high-risk group is that clinical symptoms are aty...

OBJECTIVES This prospective study investigated the effects of caffeine ingestion on the extent of adenosine-induced perfusion abnormalities during myocardial perfusion imaging (MPI). METHODS Thirty patients with inducible perfusion abnormalities on standard (caffeineabstinent) adenosine MPI underwent repeat testing with supplementary coffee intake. Baseline and test MPIs were assessed for str...

In this issue of JAPI there are two articles on the evaluation of suspected or known coronary artery disease : comparison of stress ECG and stress myocardial perfusion imaging (MPI), and adenosine stress MPI. This is a good opportunity to review the subject of evaluation of Coronary Artery Disease (CAD). The views expressed are based on my personal experience of 25 years in nuclear cardiology a...

UNLABELLED Rotenone derivatives have shown promise in myocardial perfusion imaging (MPI). CMICE-013 is a novel (123)I-labeled rotenone derivative developed for SPECT MPI. The objective of this study was to assess the image quality of CMICE-013 and compare its uptake with tetrofosmin, sestamibi, and (201)Tl in vivo in a porcine model of stress-induced myocardial ischemia. METHODS Microspheres ...

When chest symptoms recur in a patient who underwent percutaneous transluminal coronary angioplasty (PTCA), it is necessary to rule out restenosis (R). Three main noninvasive tests suggest the presence of R: exercise stress test (XT), myocardial perfusion imaging (MPI) and stress echocardiography (s-echo). The objectives of this review were: (1) to estimate the pretest probability of R as a fun...

parallel computing is a topic of interest for a broad scientific community since it facilitates many time-consuming algorithms in different application domains.in this paper, we introduce a novel platform for parallel computing by using mpi and openmp programming languages based on set of networked pcs. umzhpc is a free linux-based parallel computing infrastructure that has been developed to cr...

STUDY DESIGN A finite-element study of posterior alone or anterior/posterior combined instrumentation following total spondylectomy and replacement with a titanium mesh cage used as an anterior strut. OBJECTIVES To compare the effect of posterior instrumentation versus anterior/posterior instrumentation on transmission of the stress to grafted bone inside a titanium mesh cage following total ...

BACKGROUND We wanted to evaluate the presense of myocardial ischaemia in asymptomatic patients with high cardiovascular risk, the influencing clinical and laboratory factors and the impact of ischaemia on final management decision. MATERIAL AND METHODS We evaluated 60 asymptomatic patients with high CV risk, who underwent SPECT myocardial perfusion imaging (MPI) for detection of suspected CAD...

OBJECTIVES The aim of this study was to determine the safety of dobutamine stress myocardial perfusion imaging (MPI) obtained by real-time contrast echocardiography (RTCE) and intravenous ultrasound contrast in a large cohort of patients with suspected coronary artery disease (CAD). BACKGROUND Despite the increasing number of studies showing the potential clinical utility of myocardial contra...