introduction: this study aimed to prospectively analyze the effect of a major earthquake on the prevalence of psychological disorders such as acute stress disorder (asd), anxiety, depression, mixed anxiety depression disorder (madd), phobia, aggressive behavior, insomnia, psychosomatic disorders and also socio-demographic aspects among residents of rural community sample in east azerbaijan, ira...

To maintain well-being, all organisms require the ability to re-establish homeostasis in the presence of adverse physiological or psychological experiences. The regulation of the hypothalamic-pituitary adrenal (HPA) axis during stress is important in preventing maladaptive responses that may increase susceptibility to affective disorders. Corticotropin-releasing hormone (CRH) is a central stres...

BACKGROUND Psychosocial factors play an important role in chronic musculoskeletal pain disorders. Although psychosocial stress is likely to contribute to the development of chronic musculoskeletal pain, investigations are limited to work-related stress or examination of specific conditions such as upper limb pain. The purpose of this review is to assess the evidence for an aetiological role of ...

Parkinson's disease (PD) is the second most common neurodegenerative disorder. Although the causes of PD are still not understood, aging is a predisposing factor and metabolic stress seems to be a common trigger. Interestingly, the response to stress conditions and quality control mechanisms is impaired in PD, as well as in other neurodegenerative disorders. Downregulation of rRNA transcription...

Oxidative stress in brain is emerging as a potential causal factor in aging and age-related neurodegenerative disorders. Brain tissue from living patients is difficult to acquire; hence, animal models of aging and age-related neurodegenerative disorders, though not perfect models, have provided tissue to study the role of oxidative stress in these disorders. In this review, the central role of ...

Protein oxidation, one of a number of brain biomarkers of oxidative stress, is increased in several age-related neurodegenerative disorders or animal models thereof, including Alzheimer's disease, Huntington's disease, prion disorders, such as Creutzfeld-Jakob disease, and alpha-synuclein disorders, such as Parkinson's disease and frontotemporal dementia. Each of these neurodegenerative disorde...

OBJECTIVES To explore the separate and combined effects of work and family stress on menstrual disorders and fibrocystic changes in Chinese working women. METHODS Data were obtained from a cross-sectional study of 1,642 female railway workers. The Effort-Reward Imbalance Questionnaire and Family Stress Scale were used to measure work stress and family stress, respectively; the menstrual and b...

several investigations demonstrated that anxiety is the most common mental health disorder worldwide affected about one in 13 people. anxiety disorders are more commonly reported in western societies but it is also a main health problem in non-western countries as stress and anxiety levels have drastically increased over the last two decades. several wars in middle eastern countries in the last...

Early childhood traumatic experiences, such as childhood maltreatment, are associated with an enhanced risk of adolescent and adult alcohol and substance use disorders (defined as DSM-IV alcohol or substance abuse or dependence). Maltreated children and adolescents manifest dysregulation of major biological stress response systems including adverse influences on brain development. Dysregulation...

Art is a way to provide distance from the intense affect associated with the disaster, and a way to work around and through the natural defenses that arise when trying to link affect with cognition. The ability to create art about the threatening thoughts and feelings channels the child’s energy into the art, or into a positive task, which then can be explored safely. If these thoughts ca...