A bacterial substance has been described which gives a precipitin reaction with certain antisera to Group A streptococci. The precipitating antigen is present in various Gram-positive bacteria, including most hemolytic streptococci, staphylococci, and aerobic sporulating bacilli. It is not present in any of the Gram-negative species examined or in pneumococci, clostridia, or corynebacteria. Ana...

The authors declare no conflict of interest. The caries-controlling or preventing effect of xylitol is more than just excluding fermentable sugars from the diet. This review aims to discuss the specific effects of xylitol which could have contributed to the results of the caries trials. Xylitol promotes mineralization by increasing the flow of saliva, an effect it has in common with all sweeten...

INTRODUCTION Studies on the carriage rate of beta-hemolytic streptococci among children form an important component of public health practice to prevent disease complications such as rheumatic fever/rheumatic heart disease, nephritis, and other local or systemic infections. METHODOLOGY Throat swabs collected from asymptomatic schoolchildren were inoculated into appropriate media for isolation...

The biochemical characteristics of 172 clinical isolates of group A, C, F, or G or "nongroupable" beta-hemolytic streptococci were examined. Among these isolates, 91 were identified as beta-hemolytic strains of Streptococcus milleri. The remaining isolates included 20 Streptococcus pyogenes, 21 Streptococcus equisimilis, 37 large-colony group G streptococci, and 3 unidentified nongroupable isol...

Primary cultures of clinical material were screened for the presence of colonies suspected of being Streptococcus agalactiae (Lancefield group B). Sixty-three such cultures and 108 other isolates of beta-hemolytic streptococci (groups A, C, and G), encountered during the first 3 months of the investigation, were studied by Lancefield grouping, sodium hippurate hydrolysis, and a standardized CAM...

Perry, Dennis (Northwestern University Medical School, Chicago, Ill.) and Hutton D. Slade. Transformation of streptococci to streptomycin resistance. J. Bacteriol. 83:443-449. 1962.-A total of 43 strains of streptococci, belonging to serological groups A, B, C, D, E, F, G, H, K, L, M, N, O, and Q, and three ungroupable strains were exposed to deoxyribonucleic acid (DNA) extracted from streptomy...

Viridans group streptococci are major constituents of the normal human oral flora and are also identified as the predominant pathogenic bacteria in native valve infective endocarditis. Little information is available regarding the regulation of gene expression in viridans group streptococci, either in response to changes in the oral environment or during development of endocarditis. We therefor...

Streptococcal protective antigen (Spa) is a newly described surface protein of group A streptococci that was recently shown to evoke protective antibodies (J. B. Dale, E. Y. Chiang, S. Liu, H. S. Courtney, and D. L. Hasty, J. Clin. Investig. 103:1261--1268, 1999). In this study, we have determined the complete sequence of the spa gene from type 18 streptococci. Purified, recombinant Spa protein...

Here we present a rare case of infective endocarditis (IE) with Streptococcus canis and Chiari network in an 85 year old female living multiple dogs open skin lower extremity predisposing her to bacteremia. Underlying abnormalities the cardiac chambers such as predisposes higher incidence bacterial seeding causing IE. A is usually asymptomatic no clinical significance but can worsen prognosis I...

We present definitive evidence that at least one protective antigenic determinant on type 5 M protein of group A streptococci evokes antibody that is cross-reactive with human heart tissue. One of nine rabbits immunized with a peptide fragment of type 5 M protein (pep M5) produced antibody that cross-reacted by immunofluorescence with sarcolemmal membranes of human heart. The cross-reactive ant...