نتایج جستجو برای: stpa
تعداد نتایج: 216 فیلتر نتایج به سال:
Abstract This paper proposes a novel method to transform the results of qualitative risk analysis into numeric optimal control problem for autonomous ship navigation. Today, making high-level decisions replacing crew onboard is considered difficult, in some part due complexity managing operational risks involved. Although human supervisors, e.g., located remote operating centers are still neede...
During the last decades, collaborative robots capable of operating out their cages are widely used in industry to assist humans mundane and harsh manufacturing tasks. Although such inherently safe by design, they commonly accompanied external sensors other cyber-physical systems, facilitate close cooperation with humans, which frequently render ecosystem unsafe prone hazards. We introduce a met...
The last step of peptidoglycan polymerization involves two families of unrelated transpeptidases that are the essential targets of β-lactam antibiotics. D,D-transpeptidases of the penicillin-binding protein (PBP) family are active-site serine enzymes that use pentapeptide precursors and are the main or exclusive cross-linking enzymes in nearly all bacteria. However, peptidoglycan cross-linking ...
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