Screening for colon cancer (CC) allows for diagnosis of the early stage for malignancy and potentially reduces disease mortality as the cancer could be cured at disease earliest stages. Early detection could be desirable if accurate, practical and cost effective diagnostic measures for this cancer are available. Mortality and morbidity from colon cancer represent a major health problem involvin...

Abstract Inflammatory bowel disease (IBD) is a chronic inflammatory condition that affects around 1% of the U.S population. IBD comprised Chron’s Disease and Ulcerative Colitis (UC), with UC having higher incidence rate. believed to be caused by immune dysfunction several environmental factors. Specifically in UC, bacterial dysbiosis positively correlated colitis severity incidence. Thus, we pr...

Colorectal cancer is the second most frequent cause of death by cancer. Current gold standard screening tools are invasive, expensive, and require a lot of preparation, which result in decreased patient compliance. Screening modalities that are less invasive, have high sensitivity and specificity, inexpensive, and more accepted by the general population than the current gold standard screening ...

introduction: treatment of familial adenomatous polyposis (fap) is centered on early recognition and curative surgery with either restorative proctocolectomy with ileal-pouch-anal-anastomosis (ipaa) or colectomy with ileorectal anastomosis (ira). in this study we describe the presentation, treatment, and complications of 27 fap patients. method: all patients diagnosed with fap at our center fro...

Objectives: To determine the clinical presentation of patients Carcinoma Rectum and Different modalities treatment.
 Methodology: This was a Prospective observational study conducted in from May 2019 to April 2021 at Liaquat University Medical Health Sciences (LUMHS) Jamshoro, Sindh, Pakistan. The comprises 50 patients. All were admitted Outpatient Department (OPD). evaluated fully after h...

diagnosis of hepatitis b is routinely based on of serological assay of hepatitis b surface antigen (hbsag). occult hepatitis b virus (hbv) infection is generally defined as the detection of hbv -dna in the serum or tissues of subjects who have negative test for hbsag. transmission of hbv infection has been documented from hbsag negative, anti-hbc positive blood and organ donors. the aim of this...

Background: Gastritis is an inflammation of the protective lining stomach which has been a global burden in past decades. It can be caused by irritation, excessive alcohol use, chronic vomiting, stress, or use certain medications such as aspirin other anti-inflammatory drugs. may also Helicobacter pylori- gram-negative, microaerophilic, spiral (helical) bacterium usually found stomach.
 Me...

A 40 year old female presented with a history of cough for 1.5 years and diarrhea for 5 days. She further had a history of pinkish discoloration of skin and red-crusted papules on the anterior and posterior parts of the trunk. Chest X-ray and chest CTScan revealed focal nodular densities in lung besides an anterior mediastinal mass. The mediastinal mass was surgically removed and the pathologic...

The entire process of Clostridium difficile colonization to infection develops in large intestine. However, the real colonization pattern of C. difficile in preoperative colorectal cancer patients has not been studied. In this study, 33 C. difficile strains (16.1%) were isolated from stool samples of 205 preoperative colorectal cancer patients. C. difficile colonization rates in lymph node meta...

AIM In this study we describe the presentation, treatment, and complications of 27 FAP patients. BACKGROUND Treatment of Familial adenomatous polyposis (FAP) is centered on early recognition and curative surgery with either restorative proctocolectomy with ileal-pouch-anal-anastomosis (IPAA) or colectomy with ileo-rectal anastomosis (IRA). PATIENTS AND METHODS All patients diagnosed with FA...