نتایج جستجو برای: stirred tank bioreactor
تعداد نتایج: 23644 فیلتر نتایج به سال:
Penicillium canescens 10-10c strain was cultivated on barley straw hydrolysate as a soluble nutrient source and as inducer for xylanase production. Barley straw hydrolysate was obtained by treatment of barley straw with NaOH or hot water. In shake flask cultures, NaOH treatment was found to increase the biomass production, but was not accompanied by an increase in xylanase production. The best ...
AIMS To maximize spore production by Bacillus amyloliquefaciens B128, and its antagonism to the fungal pathogen Botrytis elliptica B061. METHODS AND RESULTS In the 5-l stirred-tank bioreactor (STR), with the 0.5 vvm aeration rate, an agitation rate of 200 rev min(-1) significantly enhanced the spore yield compared to the same in 300 rev min(-1) cultivations. In a 20-l airlift bioreactor (ALR)...
In large-scale production processes, metabolic control is typically achieved by limited supply of essential nutrients such as glucose or ammonia. With increasing bioreactor dimensions, microbial producers such as Escherichia coli are exposed to changing substrate availabilities due to limited mixing. In turn, cells sense and respond to these dynamic conditions leading to frequent activation of ...
A novel milliliter-scale bioreactor equipped with a gas-inducing impeller was developed with oxygen transfer coefficients as high as in laboratory and industrial stirred-tank bioreactors. The bioreactor reaches oxygen transfer coefficients of >0.4 s(-1). Oxygen transfer coefficients of >0.2 s(-1) can be maintained over a range of 8- to 12-mL reaction volume. A reaction block with integrated hea...
SARS-CoV-2 was identified as the pathogenic agent causing COVID-19 pandemic. Among proteins codified by this virus, Spike protein is one of most-external and -exposed. A fragment protein, named receptor binding domain (RBD), interacts with ACE2 receptors human cells, allowing entrance viruses. RBD has been proposed an interesting for development diagnosis tools, treatment, prevention disease. I...
The autocatalytic reaction between chlorite and iodide ions exhibits a remarkable range of dynamical behavior. In a stirred tank reactor it shows bistability between steady states and between a steady and an oscillatory state. It forms the core of a large family of systematically designed chemical oscillators. The chlorite-iodide system has served as the prototype reaction in the discovery and ...
Synthesis gas fermentation is a microbial process, which uses anaerobic bacteria to convert CO-rich gases organic acids and alcohols thus presents promising technology for the sustainable production of fuels platform chemicals from renewable sources. Clostridium carboxidivorans autoethanogenum are two acetogenic bacteria, have shown their high potential these processes by tolerance toward CO in...
BACKGROUND In Pichia pastoris bioprocess engineering, classic approaches for clone selection and bioprocess optimization at small/micro scale using the promoter of the alcohol oxidase 1 gene (PAOX1), induced by methanol, present low reproducibility leading to high time and resource consumption. RESULTS An automated microfermentation platform (RoboLector) was successfully tested to overcome th...
We study the stochastic model for bioremediation in a bioreactor with ideal mixing. The dynamics of the examined system is described by stochastic differential equations. We consider an optimal control problem with quadratic costs functional for the linearized model of a well-stirred bioreactor. The optimal control is based on the optimal robust state estimates. The approximate optimal solution...
The turbulent flow field generated in a baffled stirred tank was computed by large eddy simulation (LED) and the flow field was developed using the Sliding Mesh (SM) approach. In this CFD study, mixing times and power number have been determined for a vessel agitated by a 6-blade Rushton turbine. The predicted results were compared with the published experimental data. The satisfactory results ...
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