Steroids are nowadays routinely used as a long-term treatment in Duchenne muscular dystrophy (DMD). Their effects on body composition were assessed using dual X-ray absorptiometry. The study followed over 2 years 29 genetically confirmed DMD patients: 21 in the steroid-treated group and 8 in the steroid-naïve group. After 2 years of steroid treatment, the lean tissue mass values increased signi...

Steroid-induced osteoporosis is the most common cause of secondary osteoporosis and accounts for one-fifth of all osteoporosis cases. The fracture incidence under steroid may be as high as 50%. However, many patients do not undergo appropriate risk assessment and treatment before and after steroid exposure. We described a 56-year-old male patient with multiple punched-out lesions in skull unusu...

introduction: the aim of this case report was to investigate the relationship between sleep disorders and audio vestibular symptoms.   case report: a case of undiagnosed sleep disorder, presenting as a temporary auditory processing difficulty, is presented. the disorder was initially treated as sudden deafness with dizziness. a 23-year-old male patient complained of acute hearing disturbance de...

Children who suffer from steroid-resistant nephrotic syndrome (SRNS) require aggressive treatment to achieve remission. When intravenous high-dose methylprednisolone fails, calcineurin inhibitors, such as cyclosporine and tacrolimus, are used as the first line of treatment. A significant number of patients with SRNS progress to end-stage renal disease if remission is not achieved. For these chi...

Bovine adrenal cortical tissue contains a lipoidal derivative of pregnenolone (3beta-hydroxy-pregn-5-en-20-one) from which the free steroid can be liberated by treatment with alkali. Evidence for the presence of such an entity comes from examination of a nonpolar extract of tissue from which pregnenolone and its sulfate had been removed by chromatography. Treatment of the nonpolar fraction with...

Risperidone treatment in a steroid-induced psychosis case Steroids have been used effectively for many years to treat a wide variety of both acute and chronic medical conditions. Despite some well-known side effects, the association of psychiatric disorders with the use of these drugs has not been well established and documented. We describe a case of a 46-year-old man with a recent diagnosis o...

A fit 23-year-old housewife with primary infertility was first treated in 1978 by the operation of bilateral salpingostomy to correct hydrosalpinges. Having failed to conceive within two years, she was referred to a second hospital where in June 1980 laparoscopy showed a right hydrosalpinx with gross fimbriovarian adhesions. The left Fallopian tube appeared patent, but there was kinking at the ...

Steroid treatment is widely used in acute cerebral infarction yet its value is controversial. High dose dexamethasone (480 mg over 12 days) was given in a double blind, randomised controlled trial to 113 consecutive eligible patients with acute cerebral infarction admitted to an acute stroke unit. Those with stroke for more than 48 hours, known embolic sources, diabetes, and infection were excl...

OBJECTIVES This study aims to investigate whether addition of intratympanic steroid (ITS) to systemic steroid and hyperbaric oxygen (HBO) is effective in the treatment of sudden hearing loss (SHL). PATIENTS AND METHODS Between January 2008 and October 2011, 58 patients diagnosed with SHL were enrolled in the study. Twenty patients (11 males, 9 females; mean age 45.3±21 years; range 24 to 66 y...

The concept and diagnostic criteria for autoimmune pancreatitis have evolved since the first case reports published in 1960s. advances knowledge during past two decades resulted recognition of several pancreatic conditions that show, on histological evaluation, variable combinations inflammation fibrosis. In fact, comprises distinct diseases: type 1 2. Type 2 is a particular disease about which...