Vibrational strong coupling (VSC) has recently been shown to change the rate and chemoselectivity of ground-state chemical reactions via formation light–matter hybrid polaritonic states. However, observation that vibrational-mode symmetry a large influence on charge-transfer under VSC suggests considerations could be used control other types selectivity through VSC. Here, we show influences ste...

Selective cyclization of cationic alkynes is a useful tool for the synthesis biomolecules such as steroids. In their Research Article (DOI: 10.1002/chem.202204028), A. de Cózar, Arrieta and F. P. Cossío analyze computationally how nature alkyne determines size ring why conformation fused rings dictates stereoselectivity process.

New chiral BINOL-based phosphate counterions have been synthesized, fully characterized, and employed in the enantioselective gold-catalyzed dearomatization of β-naphthols with allenamides. A range densely functionalized C1-allylated naphthalenones were realized under mild conditions high levels chemo-, regio- stereoselectivity (ee up to 95 %).