نتایج جستجو برای: standard heparin
تعداد نتایج: 544724 فیلتر نتایج به سال:
STUDY QUESTION Does heparin ablate the advantageous effects of cyclic adenosine mono-phosphate (cAMP) modulators during pre-in vitro maturation (IVM) and have a deleterious effect in standard oocyte IVM? SUMMARY ANSWER Heparin interrupts energy metabolism and meiotic progression and adversely affects subsequent development of oocytes under conditions of elevated cAMP levels in cumulus-oocyte ...
Endothelialization of artificial vascular grafts is a challenging process in cardiovascular tissue engineering. Functionalized biomaterials could be promising candidates to promote endothelialization in repair of cardiovascular injuries. The purpose of this study was to synthesize hyaluronic acid (HA) and heparin-based hydrogels that could promote adhesion and spreading of endothelial progenito...
Abstract Background Coronavirus disease 2019 (COVID-19) may predispose patients to thrombotic events. The best anticoagulation strategy for continuous renal replacement therapy (CRRT) in such is still under debate. purpose of this study was evaluate the impact that different protocols have on filter clotting risk. Methods This a retrospective observational comparing two strategies (citrate only...
Background and Purpose: The most common complication of pregnancy is abortion. The etiology of recurrent pregnancy loss is not completely known. There are few therapeutics and diagnostic strategies in recurrent abortion. The aim of this study was to compare the use of heparin with aspirin vs prednisolone with aspirin in patients with recurrent pregnancy loss (RPL). Materials and Methods: T...
Heparin-induced thrombocytopenia (HIT) is an immune-mediated adverse drug effect from unfractionated or low-molecular weight heparin that results in and potentially catastrophic thrombosis. HIT occurs due to the development of platelet-activating antibodies against multimolecular complexes platelet factor 4 (PF4) heparin. Given frequency use among hospitalized patients, calculation 4Ts Score re...
Long-term in vitro maintenance of primary hepatocytes has been a challenge in hepatic tissue engineering, since these cells dedifferentiate and lose their phenotype in standard culture conditions. Some of the most successful culture systems employ collagen or Matrigel matrices. As an alternative matrix, our laboratory has been exploring the use of heparincontaining hydrogels as scaffolds for cu...
Expanded polytetrafluoroethylene(ePTFE) grafts 4mm long and 1mm in diameter were implanted into the iliac artery of 100-150g male rats using standard microvascular technique. Prior to clamp removal, the cremaster muscle was isolated as an island flap based on the iliac artery and observed using intravital fluorescence microscopy. Fields which contained a bifurcation of a first order arteriole(8...
OBJECTIVE To evaluate the safety and efficacy of heparin-coated perfusion circuits with low-dose heparinization and centrifugal pumping compared with the standard method during coronary artery bypass grafting. DESIGN Prospective, randomized, single-blind clinical trial. SETTING A primary care institution. PATIENTS Ninety patients who underwent first-time elective coronary artery bypass gr...
BACKGROUND There is an urgent need to determine whether oversulfated chondroitin sulfate (OSCS), a compound contaminating heparin supplies worldwide, is the cause of the severe anaphylactoid reactions that have occurred after intravenous heparin administration in the United States and Germany. METHODS Heparin procured from the Food and Drug Administration, consisting of suspect lots of hepari...
patients with end stage renal disease need a good vascular access for hemodialysis. arteriovenous fistula is the method of choice for vascular access in these patients. however, failure of arteriovenous fistula due to thrombosis is a major problem. the aim of this study was to evaluate the effect of the heparin on the patency of the arteriovenous fistula. this prospective interventional case co...
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