BACKGROUND We explored the views of key stakeholders to identify the ethical challenges of pragmatic trials investigating pharmaceutical drugs. A secondary aim was to capture stakeholders' attitudes towards the implementation of pragmatic trials in the drug development process. METHODS We conducted semistructured, in-depth interviews among individuals from different key stakeholder groups (ac...

Despite the high prevalence of mental illness, mental health remains a low priority in Africa. There has been no investigation of the views of stakeholders in Africa on why this is and what can be done. This paper reports a comparison of the views of stakeholders in Ghana, South Africa, Uganda and Zambia, focusing on the priority given to mental health by the government at the national and regi...

In 2004 a survey was conducted in the member states of the European Union designed to gain greater insight into the views on control strategies for foot and mouth disease, classical swine fever, and avian influenza with respect to the epidemiological, economic and social-ethical consequences of each of these animal diseases. This article presents the results of the social-ethical survey. A sele...

OBJECTIVES Treatment switching refers to the situation in a randomized controlled trial where patients switch from their randomly assigned treatment onto an alternative. Often, switching is from the control group onto the experimental treatment. In this instance, a standard intention-to-treat analysis does not identify the true comparative effectiveness of the treatments under investigation. We...

Digitalization has shaped the relationships among companies, consumers, and social participants with advancements of digital technology. As a result, companies are increasingly adopting integrating YouTube system for content dissemination engagement their customers stakeholders. This study proposes prediction model that analyzes 16 278 image datasets collected from 137 brand channels’ videos ov...

In a software development process, normally different stakeholders have different system views at different abstraction levels. This heterogeneity when applying the Model-ion levels. This heterogeneity when applying the ModelDriven Software Development approach requires the use of multiple views to represent a software system. However, EMF tools are focused on the generation of editors for one ...

Corporate social responsibility is one among the top prioritized agenda of any business organization. Many business organizations embraced CSR in a befitting manner and are evident from the number of activities undertaken by them. This paper aims to study the factors influencing the CSR initiatives of the banks in Sultanate of Oman. This is based on the major stakeholders’ perspective towards p...

Information systems research is concerned with complex imbroglios of human and non-human components. As researchers, we need ways to represent the intricacies of the different stakeholders in such situations. Traditionally, it is assumed that representing the views of human stakeholders is relatively unproblematic, but that doing this for non-humans is far more complex. This paper addresses thi...

With the advent of the smart city paradigm, modern cities have become complex systems of systems with a host of increasingly entangled dependencies and interactions among systems as well as stakeholders from multiple different domains. Efficient design, engineering, and operation of such systems is challenging due to the large number of involved stakeholders and their requirements, which might ...