BACKGROUND Forests occur across diverse biomes, each of which shows a specific composition of plant communities associated with the particular climate regimes. Predicted future climate change will have impacts on the vulnerability and productivity of forests; in some regions higher temperatures will extend the growing season and thus improve forest productivity, while changed annual precipitati...

OBJECTIVE The clinical history of bone metastases and skeletal-related events (SREs) secondary to cancers is not well understood. In support of studies of the natural history of bone metastases and SREs in Danish prostate and breast cancer patients, we estimated the sensitivity and specificity of hospital diagnoses for bone metastases and SREs (ie, radiation therapy to the bone, pathological or...

This study investigates changes in the types of storm events occurring in the Fertile Crescent as a result of global warming. Regional climate model [fifth-generation Pennsylvania State University–National Center for Atmospheric Research Mesoscale Model (MM5)–Noah] simulations are run for the first and last five years of the twenty-first century following the Special Report on Emissions Scenari...

Majority of patients with metastatic castrate resistant prostate cancer (mCRPC) develop bone metastases which results in significant morbidity and mortality as a result of skeletal-related events (SREs). Several bone-targeted agents are either in clinical use or in development for prevention of SREs. Bisphosphonates were the first class of drugs investigated for prevention of SREs and zoledroni...

BACKGROUND This study aimed to investigate the value of left atrial (LA) strain and strain rate (S/SR) by transthoracic echocardiography (TTE) in predicting left atrial appendage (LAA) stasis, in order to find a way for LAA stasis screening which is easily performed in patients with nonvalvular atrial fibrillation (NVAF). METHODS One hundred and thirty NVAF patients prepared for AF ablation w...

SMAUG (SMG) is an RNA-binding protein that functions as a key component of a transcript degradation pathway that eliminates maternal mRNAs in the bulk cytoplasm of activated Drosophila melanogaster eggs. We previously showed that SMG destabilizes maternal Hsp83 mRNA by recruiting the CCR4-NOT deadenylase to trigger decay; however, the cis-acting elements through which this was accomplished were...

Abstract Rain gauge data sparsity over Africa is known to impede the assessments of hydrometeorological risks and skill numerical weather prediction models. Satellite rainfall estimates (SREs) have been used as surrogate fields for a long time are continuously replaced by more advanced algorithms new sensors. Using unique daily dataset from 36 stations across equatorial East period 2001–18, thi...

BACKGROUND Patients with bone metastasis secondary to prostate or breast cancer or multiple myeloma are predisposed to skeletal-related events (SREs), such as surgery or radiation to the bone, pathologic fracture, and spinal cord compression. Inpatient costs of these and other SREs represent an estimated 49%-59% of total costs related to SREs. However, information on payer costs for hospitaliza...

This study presents the understanding of temporal dynamics of groundwater-surface water (GW-SW) interaction due to parameter uncertainty by using a physically-based and distributed gridded surface subsurface hydrologic analysis (GSSHA) model combined with a Monte Carlo simulation. A study area along the main stem of the Kiskatinaw River of the Kiskatinaw River watershed, Northeast British Colum...