OxLDL uptake and cholesterol efflux inhibition in macrophages play a key role in atherosclerotic plaque formation, rupture, and thrombotic ischemia. This study investigates genes implicated in OxLDL uptake (CD36, SRA), cholesterol efflux inhibition (adipophilin, ADFP), and inflammatory recruitments of leukocytes (IL-8) in plaque lesion areas (PLAs) compared to nonplaque lesion areas (NPLAs) in ...

The signal recognition particle (SRP)-mediated translocation of proteins across the RER is a GTP dependent process . Analysis of the primary amino acid sequence of one protein subunit of SRP (SRP54), as well as the a subunit of the SRP receptor (SRa), has indicated that these proteins contain predicted GTP binding sites . Several point mutations confined to the GTP binding consensus elements of...

The Data Availability statement for this paper is incorrect. The correct statement is: The unigenes information was deposited in the Sequence Read Archive (SRA) database in NCBI (Accession number, SRP055854). In the subsection Analysis of transcriptome sequencing results of the Materials and Methods section, the final sentence of the first paragraph references the incorrect accession number. Th...

• SRA-Europe • SRA-Japan • American Chemistry Council • American Physical Society • German Commission on Harmonizing Risk Standards • German Foundation for Environment and Risk Management • International Association for Probabilistic Safety Assessment and Management • Int’l Council on Systems Engineering • International Union of Toxicology • National Science Foundation • Society of Environmenta...

We characterise the class SRaCA n of subalgebras of relation algebra reducts of n-dimensional cylindric algebras (for nite n 5) by the notion of a `hyper-basis', analogous to the cylindric basis of Maddux, and by relativised representations. A corollary is that SRaCA n = SRa(CA n \ Crs n) = SRa(CA n \ G n). We outline a game-theoretic approximation to the existence of a representation, and how ...

BACKGROUND The uncertain etiology of HIV viral load (VL) blips may lead to increased use of clinical resources. We evaluated the association of self-reported adherence (SRA) and antiretroviral (ART) drug levels on blip occurrence in US Military HIV Natural History Study (NHS) participants who initiated the single-tablet regimen efavirenz/emtricitabine/tenofovir disoproxil fumarate (EFV/FTC/TDF)...

The main procedure used by clinicians to determine whether an individual may be at risk of suicidal behaviors is the suicide risk assessment (SRA). The purpose of the SRA is to identify risk and protective factors that then provide the data for the formulation of suicide risk. The suicide risk formulation (SRF) assigns a level of suicide risk that ideally leads to triage and treatment deemed ap...

Abstract The application of sense-reason-act (SRA) programming in contemporary education can ensure the development computational thinking (CT) at a more advanced level. SRA-programming has been identified as an instrumental way for learning to program robots and encourages complex concepts programming. Visual environments are diverse appearance prove be excellent teach pupils basic ideas It is...

UHRF1 is an important epigenetic regulator for maintenance DNA methylation. UHRF1 recognizes hemi-methylated DNA (hm-DNA) and trimethylation of histone H3K9 (H3K9me3), but the regulatory mechanism remains unknown. Here we show that UHRF1 adopts a closed conformation, in which a C-terminal region (Spacer) binds to the tandem Tudor domain (TTD) and inhibits H3K9me3 recognition, whereas the SET-an...

Infectivity of Trypanosoma brucei rhodesiense to humans is due to its resistance to a lytic factor present in human serum. In the ETat 1 strain this character was associated with antigenic variation, since expression of the ETat 1.10 variant surface glycoprotein was required to generate resistant (R) clones. In addition, in this strain transcription of a gene termed SRA was detected in R clones...