نتایج جستجو برای: sprout
تعداد نتایج: 1467 فیلتر نتایج به سال:
Angiogenic sprouts require coordination of endothelial cell (EC) behaviors as they extend and branch. Microtubules influence behaviors such as cell migration and cell-cell interactions via regulated growth and shrinkage. Here we investigated the role of the mitotic polarity protein LGN in EC behaviors and sprouting angiogenesis. Surprisingly, reduced levels of LGN did not affect oriented divisi...
Hydrogels with precisely controlled integrin activation dictate vascular patterning and permeability
Integrin binding to bioengineered hydrogel scaffolds is essential for tissue regrowth and regeneration, yet not all integrin binding can lead to tissue repair. Here, we show that through engineering hydrogel materials to promote α3/α5β1 integrin binding, we can promote the formation of a space-filling and mature vasculature compared with hydrogel materials that promote αvβ3 integrin binding. In...
Organ morphogenesis requires the coordination of cell behaviors. Here, we have analyzed dynamic endothelial cell behaviors underlying sprouting angiogenesis in vivo. Two different mechanisms contribute to sprout outgrowth: tip cells show strong migratory behavior, whereas extension of the stalk is dependent upon cell elongation. To investigate the function of Cdh5 in sprout outgrowth, we genera...
Sprouting angiogenesis expands the embryonic vasculature enabling survival and homeostasis. Yet how the angiogenic capacity to form sprouts is allocated among endothelial cells (ECs) to guarantee the reproducible anatomy of stereotypical vascular beds remains unclear. Here we show that Sema-PlxnD1 signaling, previously implicated in sprout guidance, represses angiogenic potential to ensure the ...
Rizky Abdulah ([email protected]) Ahmad Faried ([email protected]) Kenji Kobayashi ([email protected]) Chiho Yamazaki ([email protected]) Eka W Suradji ([email protected]) Kazuto Ito ([email protected]) Kazuhiro Suzuki ([email protected]) Masami Murakami ([email protected]) Hiroyuki Kuwano ([email protected]) Hiroshi Koyama...
A non-destructive, real time device was developed to detect insect damage, sprout damage, and scab damage in kernels of wheat. Kernels are impacted onto a steel plate and the resulting acoustic signal analyzed to detect damage. The acoustic signal was processed using four different methods: modeling of the signal in the time-domain, computing time-domain signal variances and maximums in short-t...
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