Epithelioid hemangioendothelioma (EHE) is a subtype of hemangioendothelioma which is a kind of vascular tumor with the biologic behavior between a hemangioma and a conventional angiosarcoma. Among the 6 subtypes of the hemangioendothelioma, EHE is the most aggressive member of this family and may cause distant metastasis and even death in a minority of cases. We herein present one case of EHE e...

INTRODUCTION Epitheloid hemangioendothelioma is a rare vascular soft tissue tumour of intermediate malignant potential. The tumor affects any age group, and liver is the commonest internal organ affected. Bones as calvarium, spine, tibia and femur may also be affected. The lesion can be multifocal in the liver or the same bone itself and can metastasise to lungs. Here we report a rare case of e...

epitheloid hemangioendothelioma (ehe) is an uncommon angiocentric neoplasm of intermediate malignant potential. this tumor is frequently seen in the lungs and liver, but its presentation in the oral cavity is rare. in the oral cavity, gingival region is the common sites of occurrence. we report a rare case of epitheloid hemangioendothelioma in a 48-year-old male, presenting as a growth in the u...

Eight cases of uveal malignant melanoma were studied with the electron microscope with the purpose of comparing the ultrastructural features of the three basic cell types (spindle A, spindle B, and epithelioid) originally described by Callender under the light microscope. Five of the eight tumors were of pure cell type, and three were mixed. This was undertaken because of earlier diverse opinio...

The displacement of the mitotic spindle to one side of a cell is important for many cells to divide unequally. While recent progress has begun to unveil some of the molecular mechanisms of mitotic spindle displacement, far less is known about how spindle displacement is precisely timed. A conserved mitotic progression mechanism is known to time events in dividing cells, although this has never ...

I n higher eukaryotes, the position of cytokinesis is determined by the position of the mitotic spindle (Rappaport, 1990). Generally, the spindle sits in the middle of the cell and cytokinesis produces two equivalent cells. However, many developmental processes require specific positioning of the cleavage plane and, hence, the mitotic spindle. For example, control of spindle position can be use...

6. Mentzel T, Kutzner, K. Hobnail hemangioma (“targetoid hemosiderotic haemangioma”): Clinicopathologic and immunohistochemical analysis of 62 cases. J Cutan Pathol (submitted). 7. Calonje E, Fletcher CDM, Wilson-Jones E et al. Retiform hemangioendothelioma. A distinctive form oflow-grade angiosarcoma delineated in a series of 15 cases. Am J Surg Pathol 1994; 18:115-125. 8. Santonja C, Torrelo ...

Accurate mitotic spindle positioning is essential for the regulation of cell fate choices, cell size and cell position within tissues. The most prominent model of spindle positioning involves a cortical pulling mechanism, where the minus end-directed microtubule motor protein dynein is attached to the cell cortex and exerts pulling forces on the plus ends of astral microtubules that reach the c...