The incidence of spinal cord injury (SCI) in the US is approximately 12,000 individuals annually, due to various forms of trauma and disease. (1) Previous studies show that increased force on or prolonged compression of the spinal cord results in progressive ischemia, as indicated by a reduction in spinal cord perfusion (3). Diminished flow over a prolonged period of time can cause necrosis and...

BACKGROUND Perthes Syndrome (Traumatic asphyxia) is rare, which is caused by sudden compressive chest trauma and characterized by subconjunctival hemorrhage, facial edema, craniocervical cyanosis, and petechiae on the upper chest and face. CASE PRESENTATION We present the case of a 4-year-old Caucasian girl who developed traumatic asphyxia associated with intramedullary spinal cord hemorrhage...

AIM The aim of this study was to compare the preventive effects of Etanercept, Etomidate, Erythropoietin and their combination in experimentally induced spinal cord trauma by clinical, histopathological, electrophysiological parameters and biochemical examination. MATERIAL AND METHODS 85 healthy female Wistar-Albino rats were used in this study. Rats were divided 8 trauma groups that consiste...

Pathologies of spine like trauma, infection, malignancy or congenital problems can cause disturbed structural integrity causing deformity and displacement spine. This causes compression damage on spinal cord roots, which the is supposed to protect. In such situations, needs be decompressed, realigned fused in that position, so further injury prevented. Spinal fusion a natural process healing bo...

Most surgery is designed to relieve compression of the spinal cord or spinal nerve roots. Reduction in the bore of the vertebral spinal or root canals (spinal stenosis) can occur in many conditions, and some patients have congenitally narrow canals. Osteophytic projections at the intervertebral joints (cervical spondylosis) are the commonest problem. Tumours, infection, trauma, disc protrusions...

In normal life, activity-dependent plasticity occurs in the spinal cord as well as in the brain. Like CNS plasticity elsewhere, this spinal cord plasticity can occur at many neuronal and synaptic sites and by a variety of mechanisms. Spinal cord plasticity is prominent in postnatal development and contributes to acquisition of standard behaviors such as locomotion and rapid withdrawal from pain...

Chitosan, a non-toxic biodegradable polycationic polymer with low immunogenicity, has been extensively investigated in various biomedical applications. In this work, chitosan has been demonstrated to seal compromised nerve cell membranes thus serving as a potent neuroprotector following acute spinal cord trauma. Topical application of chitosan after complete transection or compression of the gu...

A 42-year-old man with a history of benign incidental dorsal trauma 5 years earlier presented with progressive weakness of the right leg for 2 years. Clinical examination revealed decreased left-sided pain, temperature, and light touch sensation below the level of T2, right leg weakness, normal proprioception, and increased deep tendon reflexes in the right leg, in absence of bladder dysfunctio...

The hallmark of concussion injuries of the nervous system is the rapid and complete resolution of neurological deficits. Cerebral concussion has been well studied, both clinically and experimentally. In comparison, spinal cord concussion (SCC) is poorly understood. The clinical and radiological features of 19 SCC injuries in the general population are presented. Spinal cord injuries were classi...