UNLABELLED Coregistration of images from a single subject, acquired by different modalities, is important in clinical diagnosis, surgery and therapy planning. The purpose of this study was to evaluate, using a physical torso phantom, a novel, fully automated method for three-dimensional image registration of CT and SPECT, using radionuclide transmission (RNT) attenuation maps. METHODS We obta...

BACKGROUND Emerging data from published studies are demonstrating the superiority of Ga-68 PSMA PET/CT imaging in prostate cancer. However, the low yield of the Ge-68/Ga-68 from which Gallium-68 is obtained and fewer installed PET/CT systems compared to the SPECT imaging systems may limit its availability. We, therefore, evaluated in a head-to-head comparison, the diagnostic sensitivity of Ga-6...

Purpose: To study the possibility of using SPECT with a new radiopharmaceutical 99mTc-1-thio-D-glucose (99mTc-TG) for staging lymphomas. Material and methods: The included 53 patients verified diagnosis lymphoma (38 people – main group) adenopathy non-tumor origin (15 - comparison group). All group underwent 99mTc-TG SPECT, CT chest, abdominal organs all interested areas, ultrasound, biopsy fol...

UNLABELLED We examined mandibular invasion of intraoral squamous cell carcinoma by simultaneous bone and tumor dual-isotope SPECT using (99m)Tc-hydroxymethylene diphosphonate ((99m)Tc-HMDP) and (201)Tl-chloride ((201)Tl) and by CT. METHODS Early and delayed simultaneous bone and tumor dual-isotope SPECT and CT were performed on 39 patients suspected of having tumor invasion of the mandible by...

Introduction: Integration of single photon emission computed tomography (SPECT) and computed tomography (CT) scanners into SPECT/CT hybrid systems permit detection of coronary artery disease in myocardial perfusion imaging (MPI). Misregistration between CT and emission data can produce some errors in uptake value of SPECT images. The aim of this study was evaluate the influence...

CONTEXT Malignant melanoma has become an increasing interdisciplinary public health challenge worldwide. Sentinel lymph node excision (SLNE) is considered the most sensitive and specific staging test for the detection of micrometastatic melanoma in regional lymph nodes. OBJECTIVE To compare metastatic node detection and disease-free survival using single-photon emission computed tomography/co...

UNLABELLED The aim of this study was to compare the detection of bone metastases by 99mTc-methylene diphosphonate (99mTc-MDP) planar bone scintigraphy (BS), SPECT, 18F-Fluoride PET, and 18F-Fluoride PET/CT in patients with high-risk prostate cancer. METHODS In a prospective study, BS and 18F-Fluoride PET/CT were performed on the same day in 44 patients with high-risk prostate cancer. In 20 of...