The large post-reproductive life span reported for the free-living hermaphroditic nematode, Caenorhabditis elegans, which lives for about 10 days after its 5-day period of self-reproduction, seems at odds with evolutionary theory. Species with long post-reproductive life spans such as mammals are sometimes explained by a need for parental care or transfer of information. This does not seem a su...

The life span of Caenorhabditis elegans is controlled by signaling between the germline and the soma. Germ cell removal extends life span by triggering the activation of the DAF-16/FOXO transcription factor in the intestine. Here we analyze microRNA function in C. elegans aging and show that the microRNA mir-71 functions to mediate the effects of germ cell loss on life span. mir-71 is required ...

During the last decade, research has identified the endocannabinoid system (ECS) as a key regulator of essential physiological functions, including the regulation of microvascular and immune function. Indeed, increasing evidence now suggests that release of endocannabinoids and activation of cannabinoid receptors occurs during sepsis and that manipulation of the ECS may represent an important t...

ALTLAND, PAUL D., AND KIRKLAND C. BRACE. Red cell Zije span in the turfle and toad. Am. J. Physiol. 203(6) : I 188-1 I go. 1962. -Estimates of the mean life span of the red blood cells of box turtles and South American giant toads were made with glycine-2-C . l4 The mean life span of the turtle red cells probably lies between 600 and 800 days and that of the toad between 700 and 1,400 days. The...

Crosses between Bristol and Bergerac strains of the self-fertilizing hermaphroditic nematode Caenorhabditis elegans do not show the heterosis effects for life-span that complicate analysis of interstrain crosses with Drosophila or mice. Instead they yield F1 progeny with life-spans similar to those of the parent strains. By analysis of life-span variation among progeny F2 populations from such ...

Objective: Microalbuminuria and hypertension are the risk factors for diabetic nephropathy, and increased levels of liver enzymes are prevalent among diabetic patients. The aim of this research was to examine the effects of Crocus sativus supplementation on ...

Discrete spectral analysis and synthesis study the description of translation invariant function spaces over discrete Abelian groups. The basic building bricks are the exponential monomials. A remarkable result of R. J. Elliot in 1965 claimed that spectral synthesis holds on any Abelian group, which means that the exponential monomials span a dense linear subspace in any pointwise-closed transl...