نتایج جستجو برای: sortilin

تعداد نتایج: 403  

2017
Swati Venkat Adam D. Linstedt Frederick Lanni Ora Weisz

................................................................................................................................. 4 ACKNOWLEDGEMENTS .......................................................................................................... 6 INTRODUCTION ........................................................................................................................ 8 1.1...

Journal: :Arteriosclerosis, Thrombosis, and Vascular Biology 2018

2013
Christelle Devader Sophie Béraud-Dufour Thierry Coppola Jean Mazella

The neuropeptide, neurotensin, exerts numerous biological functions, including an efficient anti-apoptotic role, both in the central nervous system and in the periphery. This review summarizes studies that clearly evidenced the protective effect of neurotensin through its three known receptors. The pivotal involvement of the neurotensin receptor-3, also called sortilin, in the molecular mechani...

Journal: :Biochemical and Biophysical Research Communications 2016

Journal: :Monoclonal Antibodies in Immunodiagnosis and Immunotherapy 2015

Journal: :Arteriosclerosis, Thrombosis, and Vascular Biology 2017

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2013
Xi Chen Jianjun Chang Qiudong Deng Jie Xu Thi A Nguyen Lauren H Martens Basar Cenik Georgia Taylor Kathryn F Hudson Jaegwon Chung Kimberley Yu Phillip Yu Joachim Herz Robert V Farese Thomas Kukar Malú G Tansey

Progranulin (PGRN) is a secreted glycoprotein expressed in neurons and glia that is implicated in neuronal survival on the basis that mutations in the GRN gene causing haploinsufficiency result in a familial form of frontotemporal dementia (FTD). Recently, a direct interaction between PGRN and tumor necrosis factor receptors (TNFR I/II) was reported and proposed to be a mechanism by which PGRN ...

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