Abstract Ultrasound (US) is a kind of acoustic wave with frequency higher than 20 kHz. Learning from the echo detection ability bats and dolphins, scientists applied US for clinical imaging by sending out waves detecting echoes shifted intensities frequencies human tissue. has long played critical role in noninvasive, real-time, low-cost portable diagnostic imaging. With in-depth study multidis...

Objective(s): Low penetration depth of light is the main defect of photodynamic therapy (PDT), which could be improved by sonodynamic therapy (SDT). In this study, a combination of PDT and SDT known as sonophotodynamic therapy (SPDT) was investigated using two reverse arrangements in CT26 tumor model. Materials and Methods: The liposomal zinc phthalocyanine was synthesized and characterized. It...

Hepatocellular carcinoma (HCC) poses a severe threat to human health. The NET-1 protein has been proved be strongly associated with HCC proliferation and metastasis in our previous study. Here, we established validated the siRNA nanoparticles system conduct targeted gene therapy of xenograft vivo aid sonodynamic therapy. Then, conducted label-free proteome mass spectrometry workflow analyze for...

Cancer has become a global problem. On all continents, a great number of people are diagnosed with this disease. In spite of the progress in medical care, cancer still ends fatal for a great number of the ill, either as a result of a late diagnosis or due to inefficiency of therapies. The majority of the tumors are resistant to drugs. Thus, the search for new, more effective therapy methods con...

Sonosensitizers An aggregation-enhanced sonodynamic activity (AESA) effect is reported by Mei-Rong Ke, Jian-Dong Huang et al. in their Communication (e202113506). The AESA could open up a new avenue for the development of efficient sonosensitizers.

abstractbackground : in order to quantify effects of ultrasound irradiation parameters under therapeutic condition, especially sonodynamic therapy, it is initially necessary to evaluate inertial cavitation activity in vitro conditions therefore, in this study, the effect of 1 mhz low level ultrasound based on °oh radicals generated by acoustic inertial cavitation in aqueous solution was monitor...

sound transducer 24 mm in diameter and piezoelectrically active at both 1.0 & 2.0 MHz was used. Acoustic emission from 10% ethyl alcohol solutions were measured during insonation at acoustic intensity of 10 W/cm2 (1.0 & 2.0 MHz: 5 W/cm2 each) and the intensity of a subharmonic component at 0.5 MHz was calculated. SH phase shifting with a shift pitch not larger than 0.5 π and a shift interval ti...