Hirschsprung's disease (HD) is a development disorder of the enteric nervous system in which the altered innervation explains the inability of the aganglionic segment to relax. Impairment of cytoskeleton in SMC of aganglionic bowel has been shown. Sarcoglycan subcomplex (SG) may support the development and maintenance of muscle cells. We examined the SG subunit expression in colonic aganglionic...

Stress granule (SG) assembly represents a conserved eukaryotic defense strategy against various insults. Although essential for the ability to cope with deleterious conditions, the signaling pathways controlling SG formation are not fully understood. The energy sensor AMP-activated protein kinase (AMPK) is critical for the cellular stress response. Human cells produce two AMPK catalytic α-subun...

In fundamental analysis, it is customary to interpret an increase in the ratio of selling, general, and administrative costs to sales (the SG&A cost ratio) between two periods as a negative signal about future profitability and firm value. Implicit in this interpretation is an expectation that SG&A costs should normally move proportionately with increases or decreases in revenues, and that an i...

Saponins are sterols or triterpene glycosides that are widely distributed in plants. The biosynthesis of soybean saponins is thought to involve many kinds of glycosyltransferases, which is reflected in their structural diversity. Here, we performed linkage analyses of the Sg-3 and Sg-4 loci, which may control the sugar chain composition at the C-3 sugar moieties of the soybean saponin aglycones...

AIM To investigate factors causing diabetes recurrence after sleeve gastrectomy (SG) and duodenal-jejunal bypass (DJB). METHODS SG and DJB were performed on rats with diabetes induced by high-fat diet (HFD) and streptozotocin (STZ). HFD was used to induce diabetes recurrence at 4 wk postoperatively. Body weight, oral glucose tolerance test, homeostatic model assessment of insulin resistance (...

Stress grading (SG) layer in cable terminations limits the critical electric field and properties of SG materials are important issues which have to be considered during manufacturing and selecting procedure. In this paper, two different types of (SG) materials are analyzed by both theory and test. According to the applied theory, important parameters as: electrical resistivity, breakdown volta...

In this note we show that the moduli space M(Sg,n) of surface Sg,n of genus g with n punctures, satisfying 3g + n ≥ 5, admits no complete Riemannian metric of nonpositive sectional curvature such that the Teichmüler space T(Sg,n) is a mapping class group Mod(Sg,n)-invariant visibility manifold.

We determine the smooth locus and the locus of canonical singularities in the Cornalba compactification Sg of the moduli space Sg of spin curves, i.e., smooth curves of genus g with a theta characteristic. Moreover, the following lifting result for pluricanonical forms is proved: Every pluricanonical form on the smooth locus of Sg extends holomorphically to a desingularisation of Sg.

Hyposalivation often leads to irreversible and untreatable xerostomia. Salivary gland (SG) stem cell therapy is an attractive putative option to salvage these patients but is impeded by the limited availability of adult human tissue. Here, using murine SG cells, we demonstrate single-cell self-renewal, differentiation, enrichment of SG stem cells, and robust in vitro expansion. Dependent on ste...