Introduction Juvenile Systemic Lupus Erythematous (JSLE) is characterised by auto-antibody production directed against nuclear auto-antigens. Toll-like receptors (TLRs) are pattern recognition receptors of the innate immune system responsible for initiating an immune response against invading pathogens. TLR 3, 7-9 have been studied in SLE due to their unique ability to detect nuclear antigen. T...

In our related work, we proposed Auto Focus for stereo camera. Instead of moving optical axis Cognitive Stereo Auto Focus shifts one side image to the o side for setting focus. In the shifting process, be set on the proper place not to cause any side by visual fatigue to user. To perform low visual fatigue focusing, Cognitive Stereo Auto Focus analyzes the input scene and find how many objects ...

Auto Completion is the facility provided by most modern Integrated Development Environments and source code editors for word completion when editing source code. All auto completion mechanisms that we know of use syntactic knowledge of the programming language to provide this feature. We investigate the use of programming language agnostic prediction models to provide auto completion. We implem...

A demonstration environment is being developed at the Auto-ID Centre in Cambridge, in order to show the benefits of Auto-ID technology when applied to manufacturing control systems. In this paper, the second phase of development is examined. The first phase combined conventional control with Auto-ID information. This phase specifically looks at how Auto-ID facilitates a distributed Holonic Manu...

In this work, an auto-tuning procedure for PID controllers is presented. This autotuning procedure identifies a FOPDT model for a given process and uses an evolutionary algorithm to solve a constrained non-convex optimization problem to adjust the parameters of a PID controller with derivative filter. The auto-tuning procedure is validated with a set of process with different characteristics. P...

Auto-reactive cells-mediated immune responses are responsible for the current tissue damages during autoimmunity. Accordingly, functional modulation of auto-reactive cells has been a pivotal aim in many of recent studies. In the current study, we investigated the possibility for insertion of regulatory molecules onto auto-reactive cells through exosomal nano-shuttles as a novel approach for phe...

Autoinflammatory diseases area group of clinical conditions other than autoimmune diseases, characterized by recurrent inflammatory episodes. From apathogenetic point of view they are determined by a dys regulation of innate immunity, without involvement of specific immunity (auto reactive T cells and auto antibodies). Recently, the increased knowledge in the field of auto inflammation highligh...

BACKGROUND Adolescents with severe allergies are at particular risk of severe and fatal anaphylactic reactions. Epinephrine (adrenaline) is known to be under-utilized by teenagers. OBJECTIVE We sought to gain knowledge of adolescents' attitudes towards and experience of epinephrine auto-injectors in order to inform improvements in patient education. METHODS A qualitative study of adolescent...

BACKGROUND In view of the increasing prevalence of food allergies, there has been an associated increase in frequency of situations requiring an emergency response for anaphylaxis at the home, childcare facilities and educational institutions. OBJECTIVE To clarify the situation of adrenaline auto-injector administration in nursery/kindergarten/school, we carried out a questionnaire survey on ...