نتایج جستجو برای: sodiume alginate

تعداد نتایج: 8471  

Journal: :Tissue engineering. Part C, Methods 2009
Erin K Purcell Aparna Singh Daryl R Kipke

The purpose of this study was to evaluate the effects of alginate composition on the neurotrophic factor release, viability, and proliferation of encapsulated neural stem cells (NSCs), as well as on the mechanical stability of the scaffold itself. Four compositions were tested: a high guluronic acid (68%) and a high mannuronic acid (54%) content alginate, with or without a poly-L-lysine (PLL) c...

Journal: :Journal of applied toxicology : JAT 2008
Alessandra de Paula Alves Sousa Paulo Sergio Ferreira Barbosa Márcia Rocha Torres Alice Maria Costa Martins René Duarte Martins Renata de Sousa Alves Daniel Freire de Sousa Claudênio Diógenes Alves Letícia Veras Costa-Lotufo Helena Serra Azul Monteiro

Alginates isolated from Sargassum vulgare, present a strong antitumor activity, associated with kidney reversible damage, as analysed by histopathology of treated animals. In the present study, the renal alteration mechanisms of S. vulgare alginates were investigated using the isolated perfused rat kidney and the isolated perfused rat mesenteric blood vessel methods. The results showed that the...

Journal: :Langmuir : the ACS journal of surfaces and colloids 2011
Vishal Javvaji Aditya G Baradwaj Gregory F Payne Srinivasa R Raghavan

Biopolymers such as alginate and pectin are well known for their ability to undergo gelation upon addition of multivalent cations such as calcium (Ca(2+)). Here, we report a simple way to activate such ionic gelation by UV irradiation. Our approach involves combining an insoluble salt of the cation (e.g., calcium carbonate, CaCO(3)) with an aqueous solution of the polymer (e.g., alginate) along...

2013
Arpa Petchsomrit Namfa Sermkaew Ruedeekorn Wiwattanapatapee

Oil entrapped floating alginate beads of curcumin were developed and characterized. Cremophor EL, Cremophor RH and Tween 80 were utilized to improve the solubility of the drug. The oil-loaded floating gel beads prepared by emulsion gelation method contained sodium alginate, mineral oil and surfactant. The drug content and % encapsulation declined as the ratio of surfactant was increased. The re...

Journal: :International journal of pharmaceutics 2002
B Arica S Caliş H Kaş M Sargon A Hincal

Alginate beads containing 5-fluorouracil (5-FU) were prepared by the gelation of alginate with calcium cations. Alginate beads loaded with 5-FU were prepared at 1.0 and 2.0% (w/v) polymers. The effect of polymer concentration and the drug loading (1.0, 5.0 and 10%) on the release profile of 5-FU was investigated. As the drug load increased, larger beads were obtained in which the resultant bead...

2013
Anton Grigoryev Venkateshwarlu Gopishetty Ihor Tokarev Konstantin G. Kornev

Wet-spun stimuli-responsive composite fi bers made of covalently crosslinked alginate with a high concentration of single-walled carbon nanotubes (SWCNTs) are electroconductive and sensitive to humidity, pH, and ionic strength, due to pH-tunable water absorbing properties of the covalently crosslinked alginate. The conductivity depends on the material swelling in humid atmosphere and aqueous so...

2011
B. R. Lee K. H. Lee E. Kang S. H. Lee

The successful encapsulation of human hepatocellular carcinoma (HepG2) cells would assist applications in tissue engineering. In this paper, we have developed a method to produce chitosan-alginate microfibers within a microfluidic chip. Also, by suspending cells in the mixing solution, we fabricated HepG2 cell-laden fibers. The encapsulated HepG2 cells in the chitosan–alginate fibers were more ...

Journal: :iranian journal of microbiology 0
r nosrati molecular microbiology research center (mmrc), shahed university, tehran, i.r. iran ; department of biology, faculty of science, shahed university, tehran, i.r. iran. p owlia h saderi m olamaee i rasooli tehrani a akhavian

azotobacter vinelandii, a gamma-proteobacterium, is an obligate aerobic free-living gram-negative soil bacterium capable of fixing nitrogen. oxygen transfer rate into the cell is reduced by the increase of alginate concentrations during the course of a. vinelandii cultivation. this phenomenon provides a low intracellular oxygen concentration needed for nitrogenase activity. the aim of this stud...

Journal: :Acta crystallographica. Section F, Structural biology and crystallization communications 2012
Yukie Maruyama Takafumi Itoh Yu Nishitani Bunzo Mikami Wataru Hashimoto Kousaku Murata

Sphingomonas sp. A1 directly incorporates alginate polysaccharides through a 'superchannel' comprising a pit on the cell surface, alginate-binding proteins in the periplasm and an ABC transporter (alginate importer) in the inner membrane. Alginate importer, consisting of four subunits, AlgM1, AlgM2 and two molecules of AlgS, was crystallized in the presence of the binding protein AlgQ2. Prelimi...

Journal: :Journal of microbiology and biotechnology 2015
Hyun Jung Park Jiho Min Joo-Myung Ahn Sung-Jin Cho Ji-Young Ahn Yang-Hoon Kim

In this study, we developed lysosome-alginate beads for application as an oral drug delivery system (ODDS). The beads harboring lysosomes, which have antimicrobial activity, and various concentrations of alginate were characterized and optimized. For application as an ODDS, pH-dependent lysosome-alginate beads were generated, and the level of lysosome release was investigated by using antimicro...

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