Sodium-2-oxo-propanesulfonate (acetone sulfonate) was found to be a competitive inhibitor of acetoacetate carboxy lyase (acetoacetic decarboxylase, EC 4.1.1.4) the KI of which was numerically equal to the K, for acetoacetate at all temperatures investigated. K,,, like Kr in this case is therefore concluded to represent a dissociation constant. AH for the dissociation of either acetoacetate or a...

Sodium dodecyl benzene sulfonate (SDBS), Polyvinylpyrrolidone (PVP, MW 10 kDa), and NaCl were obtained from Sigma Aldrich. Microcalorimetry experiments were performed using a MicorCal ITC-VP at the University of Albany Proteomics Facility in Rensselaer, NY. SDBS was added to de-ionized distilled water, and placed into the injection syringe of the microcalorimeter, and added to the sample cell c...

FEW QUANTITATIVE ANALYSES of cystine in human serum protein fractions have been recorded in the literature, since cystine cannot be determined easily by microbiologic assay or paper chromatography. Brand and his coworkers (1, 2, 3) have reported the amount of cystine and cysteine in a few protein fractions using phosphotungstate and iodometric methods, but few results have been given using the ...

Tanshinone IIA sodium sulfonate (TSS) is a water-soluble derivative of tanshinone IIA, which is the main pharmacologically active component of Salvia miltiorrhiza. This study aimed to verify the preventive and therapeutic effects of TSS and its combined therapeutic effects with magnesium isoglycyrrhizinate (MI) in D-galactosamine- (D-Gal-) induced acute liver injury (ALI) in mice. The potential...

A dendrimer amphiphilic polymer (A-D-HPAM) was synthesized by aqueous solution polymerization of acrylic acid (AA), acrylamide (AM), 2-acrylamido-2-methyl-1-propane sulfonic (AMPS), hydrophobic monomer cetyl dimethyl allyl ammonium chloride (DMCAAC-16), and skeleton GA1.0, using persulfate sodium bisulfite as initiators. The chemical structure A-D-HPAM was, respectively, analyzed Fourier transf...