Oxidation of urinary pregnane-17,20-diols (17.oxogenic steroids) by sodium metaperiodate is complete within 10 mm at 55#{176}C if the concentration of sodium metaperiodate at the end of the reaction exceeds 1.5 X 10-SM. A safe excess of sodium metaperiodate is present if assay samples, after incubation for 10 mm at 55#{176}C in 3 X 10-EM ethylene glycol, give a positive test with starch-iodide ...

We assessed a nonradioactive approach to induce apoptosis in non-small cell lung cancer by a novel iodide uptake and retention mechanism. To enhance tumor apoptosis, we transduced non-small cell lung cancer cells with retroviral vectors containing the sodium iodide symporter (NIS) and thyroperoxidase (TPO) genes. Expression of NIS and TPO facilitated concentration of iodide in tumors. As a cons...

PURPOSE We sought to further localize radioiodine activity in the mouth on post-thyroid cancer therapy imaging using single-photon emission computed tomography/computed tomography (SPECT/CT). MATERIALS AND METHODS We retrospectively reviewed all patients (58) who underwent thyroid cancer therapy with iodine-131 (131I) at our institution from August 2009 to March 2011 whose post-therapy radioi...

A direct and an efficient conversion of a wide range of primary, secondary even tertiary alcohols to the corresponding iodides have been achieved under ionic liquid conditions. The method involves preparation of ionic liquid-based iminium chloride intermediate from DMF-like ionic liquid then stirring it with alcohol in present of sodium iodide. The higher yields of alkyl iodides were obtained w...

The aim of the present work is to develop two-channel emitters to probe local hydrophobicity by means of fluorescence quenching within different biomimetic supramolecular environments. To achieve this goal, the dansyl (Dns) and tryptophan (Trp) fluorophores have been covalently attached to cholic acid (CA) in order to ensure simultaneous incorporation of the two emitting units into the same com...

Although the effects of cations on the permeability of plant cells have frequently been studied, comparatively little attention has been paid to the action of anions. The writer has investigated the effects of a series of anions on the permeability of Laminaria agardhii Kjellm. Measurements were made of the electrical conductivity by the method described by Osterhout. x The salts were the pures...

OBJECTIVE To investigate the molecular mechanisms underlying the influence of alteration of iodine trapping on the prognosis of metastatic papillary thyroid carcinomas, focusing on the expression of the Na+/I(-) symporter (NIS). DESIGN We evaluated the expression of the NIS gene in a series of 11 enlarged neck lymph-node metastases of papillary thyroid carcinomas, including four patients in w...

In the presence of hydrogen peroxide and either potassium iodide, sodium chloride, or potassium bromide, purified human myeloperoxidase was rapidly lethal to several species of Candida. Its candidacidal activity was inhibited by cyanide, fluoride, and azide, and by heat inactivation of the enzyme. A hydrogen peroxidegenerating system consisting of d-amino acid oxidase, flavine-adenine dinucleot...