نتایج جستجو برای: small dense ldl

تعداد نتایج: 871324  

2001
Ronald M. Krauss

Studies employing analysis of LDL subclasses have demonstrated heterogeneity of the LDL response to low fat, high carbohydrate diets in healthy nonobese subjects. In individuals with a genetically influenced atherogenic lipoprotein phenotype, characterized by a predominance of small dense LDL (LDL subclass pattern B), lowering of plasma LDL cholesterol levels by diets with #24% fat has been fou...

Journal: :Diabetes care 2003
Karl Winkler Thomas Konrad Stefanie Füllert Isolde Friedrich Ramadan Destani Manfred W Baumstark Kristin Krebs Heinrich Wieland Winfried März

OBJECTIVE The oral antidiabetic agent pioglitazone improves insulin sensitivity and glycemic control and appears to lower atherogenic dense LDL in type 2 diabetes. Insulin resistance may occur frequently in nondiabetic patients with hypertension. This study is the first to report the effect of pioglitazone on LDL subfractions in normolipidemic, nondiabetic patients with arterial hypertension. ...

2013
Haitham M. Ahmed Mohamed B. Elshazly Seth S. Martin Michael J. Blaha Krishnaji R. Kulkarni Steven R. Jones

Background: Dense LDL phenotypes are associated with increased atherogenicity, and are commonly evaluated for the purposes of atherosclerosis research and cardiovascular risk discrimination. Objective: To examine the ability of LDL subclasses, expressed as a ratio of dense-to-buoyant subclass, to predict LDL

2013
Sunghwan Suh Hyung‐Doo Park Sang‐Man Jin Hye Jeong Kim Ji Cheol Bae So Young Park Mi Kyoung Park Duk Kyu Kim Nam H Cho Moon‐Kyu Lee

AIMS/INTRODUCTION Small dense low-density lipoprotein (sdLDL) has been suggested to be a potential risk factor for cardiovascular diseases (CVD). MATERIALS AND METHODS We carried out a prospective nested case-control study in the Korean Health and Genome Study. Participants were men and women aged 40-69 years who developed CVD (n = 313), and were matched by age and sex to controls who remaine...

Journal: :Clinical chemistry 2001
D M Hoefner S D Hodel J F O'Brien E L Branum D Sun I Meissner J P McConnell

BACKGROUND Recent evidence suggests that the presence of small, dense LDL is independently associated with increased risk of developing coronary artery disease. Current methods to subfractionate LDL are time-consuming and/or technically demanding. Therefore, we have sought the development of a less complex LDL subfractionation procedure. METHODS LDL subfractions were separated using the Quant...

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