The signal-recognition particle (SRP) mediates the translocation of membrane and secretory proteins across the endoplasmic reticulum upon interaction with the SRP receptor. In trypanosomes, the main RNA molecule is the spliced-leader (SL) RNA, which donates the SL sequence to all messenger RNA through trans-splicing. Here, we show that RNA interference silencing of the SRP receptor (SRalpha) in...

Strigolactones (SLs) are a class of plant hormones that regulate diverse physiological processes, including shoot branching and root development. They also act as rhizosphere signaling molecules to stimulate the germination of root parasitic weeds and the branching of arbuscular mycorrhizal fungi. Although various types of cross talk between SLs and other hormones have been reported in physiolo...

Stochastic local search (SLS) algorithms have been successfully applied to hard combinatorial problems from different domains. Due to their inherent randomness, the run-time behaviour of these algorithms is characterised by a random variable. The detailed knowledge of the run-time distribution provides important information about the behaviour of SLS algorithms. In this paper we investigate the...

We present a theoretical study on the terahertz (THz) optoelectronic properties of long-period InAs/GaSb type-II super lattices (SLs). The eight-band k·p model is used to calculate the electronic structures of such SLs and on the basis of band structures, the Boltzmann equation approach is employed to calculate the optical absorption coefficients for the corresponding SL systems. It is found th...

This study focuses on the use of bio-nanocomposite microspheres, consisting of carbonated hydroxyapatite (CHAp) nanospheres within a poly(L: -lactide) (PLLA) matrix, to produce tissue engineering (TE) scaffolds using a modified selective laser sintering (SLS) machine. PLLA microspheres and PLLA/CHAp nanocomposite microspheres were prepared by emulsion techniques. The resultant microspheres had ...

Inflammatory bowel disease (IBD) describes different illnesses characterized by chronic inflammation of the gastrointestinal tract. Although the pathogenic mechanisms leading to IBD are poorly understood, immune system disturbances likely underlie its development. Sphingolipids (SLs) have been identified as important players and promising therapeutic targets to control inflammation in IBD. Inte...

BACKGROUND The single-leg squat (SLS) is a common test used by clinicians for the musculoskeletal assessment of the lower limb. The aim of the current study was to reveal the kinematic parameters used by experienced and inexperienced clinicians to determine SLS performance and establish reliability of such assessment. METHODS Twenty-two healthy, young adults (23.8 ± 3.1 years) performed three...

Fast and accurate speech recognition systems bring with them the possibility of designing flexible voice driven applications. In this paper, we highlight the needs related to a voice interface and describe the implementation of a general-purpose spoken language interface, the Camegie Mellon Spoken Language Shell (CM-SLS). CM-SLS provides voice interface services to different applications runnin...

With more and more materials used in the Selective Laser Sintering (SLS) process, it is becoming necessary to use a database to manage the process efficiently. In this paper, a relational database for the SLS process is described. The database includes powdered material data, sintering parameters, machine characteristics, mechanical properties and surface quality of prototypes. Use of this data...

An interesting strategy called configuration checking (CC) was recently proposed to handle the cycling problem in local search for Minimum Vertex Cover. A natural question is whether this CC strategy also works for SAT. The direct application of CC did not result in stochastic local search (SLS) algorithms that can compete with the current best SLS algorithms for SAT. In this paper, we propose ...