A double blind crossover trial with active or placebo slow release theophylline (Slo-phyllin) in children with asthma aged up to 4 years is described. Although no difference in symptom scores was shown, other differences in favour of active treatment were noted. We conclude that this preparation is of benefit in the management of the wheezing preschool child. The value of symptom scores as an i...

STUDY OBJECTIVE Oral theophylline treatment may be helpful in controlling severe asthma during pregnancy. This treatment, however, has been suspected of causing both complications and malformations. The objective of this investigation was to study the influence of theophylline treatment on the course of pregnancy and delivery and on maternal and infant health. SETTING Respiratory unit, antena...

Applying 6 3 Cu N M R technique, we observed exchange between the nonequivalent copper sites in crystalline Cu6PS5Br, known as a member of the mineral "argyrodite". Below 200 K, where the motion of the copper (I) ion is slow, we could distinguish several nonequivalent copper sites. On increasing the temperature, the chemical exchange between the nonequivalent cation sites was seen on the " C u ...

Although the prevalence of caries has decreased dramatically over the past decades, it has become a polarised disease, with most of subjects presenting low caries levels and few individuals accounting for most of the caries affected surfaces. Thus it become evident for the need of clinical approaches directed at these high-risk patients, in order to overcome problems related to compliance and l...

There have been several recent developments in slow-release fertilizers. These materials supply nutrients continuously over an extended period in contrast to water soluble fertilizers which are immediately available after incorporation in moist soil. Slow-release fertilizers are not subject to rapid leaching loss and do not easily burn plants from over-application. The major need for slow relea...

Dental caries still continues to be a problem for majority of individuals and it can be a serious problem for medically compromised, developmentally disabled and elderly individuals. Water fluoridation, systemic and topical fluorides have been used for many years to supply supplemental fluoride to combat dental caries. The latest fluoride research is investigating the use of slow release device...

Nitrogen management practices have an effect on crop yields but they can also have a negative impact on the environment. Practices such as banding fertilizer and/or split-applying total nitrogen needs per acre offer a more efficient use of nitrogen by significantly reducing nitrate leaching potential. Heavy rains occurring when plants are small and nitrogen demands are low can also increase nit...

copper is most toxic metal in marine organisms. characterization of protein occurring in the metabolically active tissues of muscle (mu), hepatopancreas (hp) and gills (gl) of the spiny lobster, panulirus homarus homarus on exposure to two sub-lethal doses (9.55 and 19.1 µg/l) of copper were studied for 28 days of exposure (doe). the electrophoretic pattern of muscle, hepatopancreas and gill pr...

Thymol, an important and advantageous component of many essential oils, has been applied as an antimicrobial agent in animals. To increase the duration of action of this compound in ruminants, it was decided here to prepare a controlled release carrier for thymol. Hydroxy propyl methyl cellulose (HPMC) and ethyl cellulose (EC) were used as the matrix polymer here. Mixtures of thymol with eight ...