5-HT3A receptors select among permeant ions based on size and charge. The membrane-associated (MA) helix lines the portals into the channel's cytoplasmic vestibule in the 4-Å resolution structure of the homologous acetylcholine receptor. 5-HT3A MA helix residues are important determinants of single-channel conductance. It is unknown whether the portals into the cytoplasmic vestibule also determ...

One way of recovering information about the initial conditions of the Universe is by measuring features of the cosmological density field which are preserved during gravitational evolution and galaxy formation. In this paper we study the total number density of peaks in a (galaxy) point distribution smoothed with a filter, evaluating its usefulness as a means of inferring the shape of the initi...

PURPOSE Flattening filter free (FFF) beams generated by medical linear accelerators are today clinically used for stereotactical and non-stereotactical radiotherapy treatments. Such beams differ from the standard flattened beams (FF) in the high dose rate and the profile shape peaked on the beam central axis. Definition of new parameters as unflatness and slope for FFF beams has been proposed b...

annihilation or reduction of each kind of noise blended in correct data signals is a field that has attracted many researchers. it is a fact that fuzzy theory presents full capability in this field. fuzzy filters are often strong in smoothing corrupted signals, whereas they have simple structures. in this paper, a new powerful yet simple fuzzy procedure is introduced for sharpness reduction in ...

In this study, a structure that can effectively prevent overtopping caused by abnormal rainfall was installed in deteriorative agricultural reservoir, and seepage characteristics were compared analyzed through model experiments numerical analysis. The experimental conditions observed installing stepped gabion, vertical parapet combination with gabion retaining wall, geomembrane, core on the dam...

We study algebraic properties of categories of Merotopic, Nearness, and Filter Algebras. We show that the category of filter torsion free abelian groups is an epireflective subcategory of the category of filter abelian groups. The forgetful functor from the category of filter rings to filter monoids is essentially algebraic and the forgetful functor from the category of filter groups to the cat...

in this article we introduce the concept of $z^circ$-filter on a topological space $x$. we study and investigate the behavior of $z^circ$-filters and compare them  with corresponding ideals, namely, $z^circ$-ideals of $c(x)$,  the ring of real-valued continuous functions on a completely regular hausdorff space $x$. it is observed that $x$ is a compact space if and only if every $z^circ$-filter ...

In this paper, we proposed a novel structure for designing all optical filter based on photonic crystal structure. In designing the proposed filter, we simply employed a point defect localized between input and output waveguides as wavelength selecting part of the filter. The initial form of this filter is capable of selecting optical waves at =1560 nm, the transmission efficiency of the filte...